'Protein family' diaporamas de présentation

A Tale of Two Worms: Comparing the Genomes of C. elegans & C . briggsae

A Tale of Two Worms: Comparing the Genomes of C. elegans & C . briggsae. Lincoln Stein Cold Spring Harbor Laboratory. My Lab. International HapMap Project. Find common regions of genetic variation in human population to reduce cost of genetic association studies.

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506 views • 41 slides

Classifying the protein universe

Synapse-Associated Protein 97. Classifying the protein universe. Wu et al, 2002. EMBO J 19:5740-5751. Domain Analysis and Protein Families. Introduction What are protein families? Protein families Description & Definition Motifs and Profiles The modular architecture of proteins

523 views • 37 slides

Dot Plots, Path Matrices, Score Matrices

Dot Plots, Path Matrices, Score Matrices. Sequence A. V. T. R. I. V. H. V. N. S. I. L. P. S. T. N. I. L. S. V. I. L. S. T. R. I. Sequence B. V. I. L. P. E. F. S. T. diagonal lines give equivalent residues. Sequence A. V. T. R. I. V. H.

491 views • 35 slides

Demo: Protein Information Resource

Demo: Protein Information Resource. March 28, 2002 NIH Proteomics Workshop Bethesda, MD Lai-Su Yeh, Ph.D. Protein Scientist, National Biomedical Research Foundation. Database Demo. NREF Database http://pir.georgetown.edu/pirwww/search/pirnref.shtml iProClass Database

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Translation of nucleotide sequences

433 views • 28 slides

Some frequently-used Bioinformatics Tools

Some frequently-used Bioinformatics Tools . Konstantinos Mavrommatis Prokaryotic Superprogram. Outline. Pairwise Alignment Global/Local, Scoring BLAST, BLAT, SIM, LALIGN, Dotlet, Ublast Multiple Sequence Alignment

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Biology 224 Instructor: Tom Peavy March 13 & 18, 2008

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Selecting Targets which Probe Family and Function Space

Selecting Targets which Probe Family and Function Space. How many protein families can we identify in the genomes with/without structures? Which families should we target to maximise the structural coverage of the genomes? Can we optimise function coverage?. CATH , Gene3D.

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Objectives for protein section II

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School B&I TCD Bioinformatics

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Doochul Kim (Seoul National University, Korea) based on K.I- Goh, B. Kahng and D. Kim

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molecular biology database2

molecular biology database2. Databases at ExPASY. Prominent databases: SWISS-PROT PROSITE ENZYME SWISS-2DPAGE SWISS-3DIMAGE, SWISS-MODEL Repository. SWISS-PROT - Protein knowledgebase.

310 views • 18 slides

Protein Family Classification using Sparse Markov Transducers

Protein Family Classification using Sparse Markov Transducers. Proceedings of Eighth International Conference on Intelligent Systems for Molecular Biology (ISMB2000) , pp. 134-145 E. Eskin, W.N. Grundy, and Y. Singer Cho, Dong-Yeon. Abstract.

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PIRSF Classification System

PIRSF Classification System. Protein Classification and Functional Annotation. PIRSF: Evolutionary relationships of proteins from super- to sub-families Homeomorphic Family : Homologous proteins sharing full-length similarity and common domain architecture Significance

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Constrained Multiple Structure Feature Alignment (CMSFA)

Constrained Multiple Structure Feature Alignment (CMSFA). ??? , ??? , ??? , ??? , ??? , ??? NCS2005. Abstract.

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Pfam( P rotein fam ilies )

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Making sense of a gene fusion event in Proteobacteria

Making sense of a gene fusion event in Proteobacteria. Dawn Anderson (Berea College) Rob Barber (U of Wisconsin Parkside) Teresa Johnson (College of Wooster). A promiscuous protein domain (and coding region). The GAT-1 family is comprised of proteins containing a Type-1 glutamine

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Markov Cluster (MCL) algorithm http://micans.org/mcl/

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Spectral matching identifies peptides by comparing spectra with libraries of identified spectra

D1. D2. D3. D4. I0. I1. I2. I4. I3. Begin. b1. y1. b2. y2. End. HMMatch : Peptide Identification by Spectral Matching of Tandem Mass Spectra Using Hidden Markov Models. US HUPO.

187 views • 1 slides