'Protein functions' diaporamas de présentation

Disorders of Peroxisome Biogenesis (PBD)

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Warm-Up

Warm-Up. What are the 4 classes of macromolecules? Give an example of each type of macromolecule. Warm-Up. What are the 4 levels of protein structure? What bonds are formed in each level? Which protein was involved in the curds & whey lab yesterday?

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ie. amino acid ? peptide ? polypeptide ? protein

ie. amino acid ? peptide ? polypeptide ? protein. larger. smaller. + H 2 O. +. + H 2 O. +. Dehydration synthesis/condensation reaction. Dehydration Synthesis. Hydrolysis. Hydrolysis reaction. Carbohydrates. Differ in position & orientation of glycosidic linkage.

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Protein Functions; Enzyme Properties

Protein Functions; Enzyme Properties. Andy Howard Introductory Biochemistry, Fall 2009 15 September 2009. Proteins and enzymes. Proteins perform a variety of functions, including acting as enzymes. Visualizing structure The Protein Data Bank Tertiary & quaternary structure

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125:583 Protein Arrays (Biosurfaces for Proteome Research)

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Chapter 4 The Chemical Composition of Proteins

Chapter 4 The Chemical Composition of Proteins. Homework II (cont’d): Ch. 6 problems 6, 7, 8 (optionally 10) and Ch. 7 problems 3, 6, 7, 9, 10 (optionally 12) a useful site: www.cbi.pku.edu.cn Use blast search in database swissprot

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Chapter 2 Section 3: The Chemistry of Life

Chapter 2 Section 3: The Chemistry of Life. Atom. Defn: the smallest unit of _______________ __________________________________ and consisting of a dense, central, positively charged nucleus surrounded by a system of electrons. Element. A substance made from _____________________.

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A Global View of the Protein Structure Universe and Protein Evolution

A Global View of the Protein Structure Universe and Protein Evolution. Sung-Hou Kim University of California, Berkeley, CA U.S.A. June 27, 2006. Topics. Global view of the protein structure universe II. Mapping of protein functions on the structural universe

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Master Course Sequence Alignment Lecture 9 Motif searches

C. E. N. T. E. R. F. O. R. I. N. T. E. G. R. A. T. I. V. E. B. I. O. I. N. F. O. R. M. A. T. I. C. S. V. U. Master Course Sequence Alignment Lecture 9 Motif searches. Pattern matching.

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Amino Acids and Proteins B.2

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Chapter 20 Evolution of Genes and Traits

Chapter 20 Evolution of Genes and Traits. Darwinian evolution, mutations and molecular evolution, a case study in natural selection, morphological evolution; the origin of new genes and protein functions. Major principles of Darwinian evolution.

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MAPPING OF SEQUENCES TO GENE ONTOLOGY

MAPPING OF SEQUENCES TO GENE ONTOLOGY. GO consortium. Current Ontologies. Molecular function : tasks performed by gene product Biological process : broad biological goals accomplished by ordered assemblies of molecular functions

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ENZYMES

ENZYMES. WHAT IS AN ENZYME. ENZYMES are proteins that act as a biological catalyst CATALYSTS increase the rate of a chemical reaction without being CONSUMED by that reaction. WHAT IS AN ENZYME. REMEMBER our 4 MACROMOLECULES: Carbohydrates Lipids Proteins Nucleic acids

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Protein World

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Analogous

Analogous. Homologous vs Analogous . Vestigial Structures. W hile the forelimbs slowly evolved into flippers, the hind limbs Slowly disappeared and all that is left is a few tiny bones. Several Examples. The Appendix. Wisdom teeth in humans. Blind Cave Fish.

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Three-dimensional Reconstruction of the PA200-20S Proteasome Complex by Cryo-EM

Three-dimensional Reconstruction of the PA200-20S Proteasome Complex by Cryo-EM Joaquin Ortega. Ph.D. Biochemistry & Biomedical Sciences Mcmaster University. Hamilton, ON. Canada. Protein Quality Control System. From: Wickner et al. Science (1999). v. 286, 1888-1893.

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Workshop Bioinformatics and Computational Biology

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Proteins

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proteomics

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1. Introduction Proteins play an essential role in nearly all cell functions.

Protein Flexibility Modeling Using Kernel Methods X ue-wen Chen and Jeremy Chen Bioinformatics and Computational Life Science Laboratory, ITTC Department of Computer Science, The University of Kansas, Lawrence, KS 66045 E?mail: xwchen@ku.edu. 3. Relevant Work Collective mode based

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