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Lecture 17: Model-Free Linkage Analysis

Lecture 17: Model-Free Linkage Analysis. Date: 10/17/02 IBD and IBS IBD and linkage Fully Informative Sib Pair Analysis Sib Pair Analysis with Missing Info. Limitations of the Model-Based Methods. Loss of power when model misspecified in multilocus scenario.

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Complex Traits

Complex Traits. Intro. Many traits (over 6000 in humans) are inherited in a simple Mendelian fashion: autosomal or sex-linked, dominant or recessive. These patterns are fairly easy to see when pedigrees are examined.

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Lecture 17: Model-Free Linkage Analysis

Complex Traits