'Signal peptide' diaporamas de présentation

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PROTEIN LOCALIZATION and SECRETION

PROTEIN LOCALIZATION and SECRETION. Collinearity. Order of nucleotides in the DNA gene would correlate with the order of amino acids in the corresponding polypeptide Charles Yanofsky showed this property using trpA, a gene that encodes a subunit of tryptophan synthetase

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Computing Patterns in Biology

Systems biology - figure out circuits. of regulation, predict outcome ... Very simple to find these patterns - can even use the

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Protein Functional Annotation

Protein Functional Annotation. Dr G.P.S. Raghava. Annotation Methods. Annotation by homology (BLAST) requires a large, well annotated database of protein sequences Annotation by sequence composition simple statistical/mathematical methods Annotation by sequence features, profiles or motifs

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Chapter 5.5 Protein sorting

Chapter 5.5 Protein sorting. The Structure of Proteins.

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Protein Functional Annotation

Protein Functional Annotation. Dr G.P.S. Raghava. Annotation Methods. Annotation by homology (BLAST) requires a large, well annotated database of protein sequences Annotation by sequence composition simple statistical/mathematical methods Annotation by sequence features, profiles or motifs

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Compartments in the eukaryotic cell

Compartments in the eukaryotic cell. Protein targeting/localization signals. Signal peptide Mitochondrial targeting peptide Chloroplast targeting peptide LPxTG sorting signal Peroxisomal targeting signal (PTS2) Signal anchor Nuclear localization signal ER/Golgi retention signal

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From Gene to Protein

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Hidden unit weights in network model correlations

Hidden unit weights in network model correlations. Compartments in the eukaryotic cell. Protein targeting/localization signals. Signal peptide Mitochondrial targeting peptide Chloroplast targeting peptide LPxTG sorting signal Peroxisomal targeting signal (PTS2) Signal anchor

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Protein Synthesis

5b . Students know how to apply base-pairing rules to explain precise copying of DNA during semiconservative replication and transcription of information from DNA into mRNA.

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Eukaryotic Secretome Prediction and Knowledge-Base Development

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From Gene to Protein

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Sung Youn Lee, PhD. Student Veterinary collage, Room 320 02 450 3719, 016 293 6059

Cell Biology 10 - Review. Sung Youn Lee, PhD. Student Veterinary collage, Room 320 02 450 3719, 016 293 6059 leevet@paran.com. Schwann cell -PNS. Oligodendrocyte -CNS. To groove. Allowing the myosin heads to make contact with the released sites of the actin monomer.

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Khar Heng Choo & Joo Chuan Tong (I2R) Shoba Ranganathan

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Support Vector Machine-based Transmembrane Protein Topology Prediction Tim Nugent

Support Vector Machine-based Transmembrane Protein Topology Prediction Tim Nugent. Alpha-helical Transmembrane Proteins. Transmembrane proteins fulfil many critical cellular functions. Comprise about 30% of the human proteome.

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Eukaryotic Genome Annotation

Eukaryotic Genome Annotation. Asaf Salamov, Fungal Genomics Program US DOE Joint Genome Institute, Walnut Creek, CA. Started with Human Genome Project. IMG. MycoCosm. 150+ annotated eukaryotic genomes. genome.jgi.doe.gov. Annotation Pipeline. Gene families Gene expression Phylogenomics

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Protein Targetting Prokaryotes vs. Eukaryotes Mutations

Protein Targetting Prokaryotes vs. Eukaryotes Mutations. AP Biology Unit 2. Protein Targetting. Secretory proteins have molecular tags that help direct them to the ER = signal peptide

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Foreign Gene Expression and Protein Production in Prokaryotes and Eukaryotes

Foreign Gene Expression and Protein Production in Prokaryotes and Eukaryotes. Prokaryotic Expression Systems Fusion Proteins Biofilms Secretion Eukaryotic Expression Systems Posttranslational modifications (PTMs). Prokaryotic Expression Systems.

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Foreign Gene Expression and Protein Production in Prokaryotes and Eukaryotes

Foreign Gene Expression and Protein Production in Prokaryotes and Eukaryotes. Prokaryotic Expression Systems Fusion Proteins Biofilms Secretion Eukaryotic Expression Systems Posttranslational modifications (PTMs). Prokaryotic Expression Systems.

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Spag11a signal peptide prediction

Additional file 4: Figure S3. Spag11a signal peptide prediction. Measure Position Value Cutoff signal peptide? max. C 20 0.858 max. Y 20 0.863 max. S 8 0.941 mean S 1-19 0.857 D 1-19 0.860 0.450 YES Name=Sequence SP='YES'

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