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Multiple sequence alignment MSA

Multiple sequence alignment MSA

Multiple sequence alignment MSA. What is MSA. Comparison of many (i.e., >2) sequences local or global. Why MSA. Biological sequences often occur in families. Homologous sequences often retain similar structures and functions. related genes within an organism

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972 views • 48 slides
Nothing in ( computational ) biology makes sense except in the light of evolution

Nothing in ( computational ) biology makes sense except in the light of evolution

Using (and abusing) sequence analysis to make biological discoveries . Nothing in ( computational ) biology makes sense except in the light of evolution. after Theodosius Dobzhansky (1970). Significant sequence similarity is evidence of homology.

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787 views • 43 slides
I SUPPORT OPEN ACCESS PubMed Central www.pubmedcentral.nih.gov/ Public Library of Science www.publiclibraryofscience.or

I SUPPORT OPEN ACCESS PubMed Central www.pubmedcentral.nih.gov/ Public Library of Science www.publiclibraryofscience.or

I SUPPORT OPEN ACCESS PubMed Central www.pubmedcentral.nih.gov/ Public Library of Science www.publiclibraryofscience.org Nucleic Acids Research nar.oupjournals.org/. Thanks to the authors and reviewers who support NAR Please introduce yourselves!. rebase.neb.com/rebase/rebase.html.

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410 views • 26 slides
Bioinformatics for biomedicine Seminar: Sequence analysis of a favourite gene

Bioinformatics for biomedicine Seminar: Sequence analysis of a favourite gene

Bioinformatics for biomedicine Seminar: Sequence analysis of a favourite gene. Lecture 5, 2006-10-17 Per Kraulis http://biomedicum.ut.ee/~kraulis. What is bioinformatics? Basic databases and tools Sequence searches: BLAST, FASTA Multiple alignments, phylogenetic trees

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282 views • 18 slides

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