'Small interfering rna' diaporamas de présentation

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Gene regulation

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Regulating gene expression Goal is controlling Proteins How many? Where? How active?

Regulating gene expression Goal is controlling Proteins How many? Where? How active? 8 levels (two not shown are mRNA localization & prot degradation). mRNA PROCESSING Primary transcript is hnRNA Is capped, spliced and poly-adenylated before export to cytosol Many are also edited

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RNAi

RNAi. What is RNAi?. RNA-based mechanisms of gene silencing. These siRNAs are bound by a protein-RNA complex called the RNA-induced silencing complex (RISC). Mello and Fire.

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siRNA Data Collection and Analysis

siRNA Data Collection and Analysis. Blake Adams CS 6985 12/08/2004. What is RNA silencing? Data Collection Data Extraction Articles of Interest siRNA scoring technique siRNA scoring program Some results Conclusion. Overview. How RNA Interference (RNAi Silencing) Works.

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Small interfering RNA

Small interfering RNA. Petunias. Chalcone synthase. White pigment. Purple pigment. Producing a deep purple petunia. Chalcone synthase. White pigment. Purple pigment. More enzyme produced and more pigment formed. Insert gene encoding chalcone synthase. More mRNA synthesised.

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????? ??????? ???? 1 ????? ?????? ????? Tue, ????? ????? Office : LS303, ??? 3595. * ? ???? ???????????????????????? ????????????????? * ???? 40~45 ?????????? 15~20 ??? * ????????????????????????????? ???????? ??? Presentation: 60%

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