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Engineering a simpler pheromone response pathway

Engineering a simpler pheromone response pathway. Alex Mallet Endy Lab MIT. Regulation of pheromone pathway (Dohlman and Thorner, 2001). Transcriptional complexity. Transcriptional response ~ 200 genes upregulated, ~200 genes downregulated after exposure to pheromone (Roberts et al, 2000)

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Engineering a simpler pheromone response pathway