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Exploring complex diseases using genome-wide association: challenges and strategies

Exploring complex diseases using genome-wide association: challenges and strategies

Exploring complex diseases using genome-wide association: challenges and strategies. Li Jin, Ph.D. Fudan University CAS-MPG Partner Institute for Computational Biology. HGM2006, Helsinki. A G C. G G C. Gly. Ser. Positional Cloning. HGM2006, Helsinki. Linkage Disequilibrium.

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614 views • 51 slides
Haplotype Blocks: or how I learned to stop worrying and love the recombination hotspot

Haplotype Blocks: or how I learned to stop worrying and love the recombination hotspot

Haplotype Blocks: or how I learned to stop worrying and love the recombination hotspot. Benjamin Neale, David Evans, Pak Sham Boulder, Colorado March 2005. http://webpages.charter.net/harshec/lego/images/simpsons/milhouse_0.jpg. Where we are going. Multilocus mapping

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572 views • 39 slides
Genetic Statistics Lectures ??? Evaluation of a region with SNPs

Genetic Statistics Lectures ??? Evaluation of a region with SNPs

Genetic Statistics Lectures ??? Evaluation of a region with SNPs. You found an associated SNP. From where to where the association can extend? The observed association on the particular SNP is strongest? Is there any SNP in LD associated more?. ??????????. ?????????????????? ???????????.

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204 views • 20 slides
Association Studies, Haplotype Blocks and Tagging SNPs

Association Studies, Haplotype Blocks and Tagging SNPs

Association Studies, Haplotype Blocks and Tagging SNPs. Prof. Sorin Istrail CSCI2950-L Tues. & Thur. 2:30-3:50p.m. CIT room 241. Control Non-responder. Disease Responder. Allele 0. Allele 1. Marker A: Allele 0 = Allele 1 =. Marker A is associated with Phenotype. Association studies.

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173 views • 17 slides
The HapMap Project and Haploview

The HapMap Project and Haploview

The HapMap Project and Haploview. David Evans Ben Neale University of Oxford Wellcome Trust Centre for Human Genetics. Human Haplotype Map. General Idea : C haracterize the distribution of Linkage Disequilibrium across the genome.

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285 views • 16 slides

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