'Ubiquitin' diaporamas de présentation

Immune dysfunction in trauma and sepsis: Novel aspects of ubiquitin

Immune dysfunction in trauma and sepsis: Novel aspects of ubiquitin. Matthias Majetschak, MD, PhD DeWitt Daughtry Family Department of Surgery Div. of Trauma and Surgical Critical Care. Ubiquitin. Immune dysfunction in trauma and sepsis: Novel aspects of ubiquitin. Immune dysfunction

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The Ubiquitin Proteosome Pathway

The Ubiquitin Proteosome Pathway. Swati Pradhan Mayura Dange Vidyadhar Daithankar. Overview. Background Protein misfolding & degradation Ubiquitin & proteosome structure Ubiquitin Proteosome Pathway Mechanism Structures of enzymes involved in pathway

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Proteomics and posttranslational modifications Xiaozhong Peng

Proteomics and posttranslational modifications Xiaozhong Peng Department of Molecular Biology and Biochemistry National Laboratory of Medical Molecular Biology CAMS & PUMC. Protein Translation. Ribosome Structure. The Initiation of Translation.

607 views • 40 slides

Metabolism of amino acids, porphyrins

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Performance and Scaling Effects of MD Simulations using NAMD 2.7 and 2.8

Performance and Scaling Effects of MD Simulations using NAMD 2.7 and 2.8. Grad OS Course Project Kevin Kastner Xueheng Hu. Introduction. Molecular Dynamics (MD) MD is extremely computationally intensive Primarily due to the sheer size of the system

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Regulation of the Myosin-Directed Chaperone UNC-45 by a Novel

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Welcome

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rndsystems/mini_review _detail_objectname_MR04_ TollLikeReceptorFamily.aspx

http://genomebiology.com/2000/ 1/6/REPORTS/0079/figure/F1. http://www.rndsystems.com/mini_review _detail_objectname_MR04_ TollLikeReceptorFamily.aspx. NFkB. http://www.stat.rice.edu/~siefert/Research/NfKB.html.

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Ubiquitin and Ub-like proteins

Ubiquitin and Ub-like proteins. 18-1. Ubiquitin and ubiquitin-like proteins - background - the ubiquitin fold - ThiS, molybdopterin synthase Degradation - degradation of newly-synthesized proteins. Ubiquitin. ubiquitin is always made as a fusion protein:

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GH 1

1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. N.C. GH 1. GH 2. Scn 1. Scn 2. Mlc 1. Mlc 2. IFN a 1. Ubiquitin. Atlantic salmon.

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100

WT ub. ub K48R. ub K63R. 0. 2. 0. 2. 0. 2. hrs. 170. 100. 72. 54. 46. 35. 24. 17. Supplemental Figure 1. In vitro ubiquitylation assay with ubiquitin variants. The ubiquitylation complex consisting of GST-RGLG2, MMZ2

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Ubiquitin-Proteasome Pathway

The ubiquitin-proteasome pathway (UPP) is one of the major destruction ways to control the activities of different proteins. The function of UPP is to eliminate dysfunctional/misfolded proteins via the proteasome, and these specific functions enable the UPP to regulate protein quality in cells. Therefore defects in UPP are expected to disturb cellular homeostasis and are detrimental to cell survival.

39 views • 1 slides