Spinal Cord Injury

1. Spinal Cord Injury Topics in Bioengineering

3. http://neuroscience.uth.tmc.edu/s2/chapter03.html

4. Characterization of the cell populations in vitro bFGF BMP-4 CNTF Nuclei GFAP (differentiation) Olig2 (injury) Markers of astrocyte differentiation/ astroglial lineage Davies et al (2011) PLoS One. Figure 1

5. Characterization of the cell populations in vitro 9W-1 9W-2 Glial scar formation/ injury response Davies et al (2011) PLoS One. Figure 1

6. Transplant morphology: Human GDA survival and support of axon growth within DLF injuries NF+ density: BMP: 14.79 ± 3.05 CNTF: 7.75 ± 2.28 Davies et al (2011) PLoS One. Figure 2 and Suppl Figure 1; http://vanat.cvm.umn.edu/neurLab2/SpCdWhite.html

7. Cell migration and GFAP staining within injuries Arrowheads indicate cell bodies Max rostral/caudal migration: CNTF: 3.24/ 3.96 mm BMP: 2.52/ 2.16 mm Davies et al (2011) PLoS One. Figure 3

8. Functional assessment after implantation of hGDAsBMPhGDAsCNTF or hGCPs Grid walk test: http://www.pnas.org/content/suppl/2007/02/19/0611723104.DC1/11723Movie1.mov Davies et al (2011) PLoS One. Figure 5

9. Neuroprotection and survival White = NeuN (neuron survival marker) Davies et al (2011) PLoS One. Figures 6 and 7

11. The Injury Model Van den Brand et al (2012) Science. Suppl Figure 1

12. The Robotic Postural Interface Van den Brand et al (2012) Science. Suppl Figure 2

13. Multi-System Neuroprosthetic Training System Van den Brand et al (2012) Science. Suppl Figure 3

14. Locomotion after training Van den Brand et al (2012) Science. Figure 1

15. Locomotion after training http://www.sciencemag.org/content/suppl/2012/05/30/336.6085.1182.DC1/1217416s1.mov Van den Brand et al (2012) Science. Supplementary Movie 1

16. Neural circuit remodeling Van den Brand et al (2012) Science. Figure 2

17. Neural circuit remodeling Van den Brand et al (2012) Science. Figure 3

18. Neural circuit remodeling Van den Brand et al (2012) Science. Figure 4