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Pharmacology designing experiment. Effects of Diazepam by oral administration with water, milk, grapefruit juice, alcohol, tea. Group member: Christine Tiffany Terry Homer Tutor: Professor lv, Professor Xiong. Presentation Outline. 1. Introduction 1.1 case 1.2 questions
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Pharmacology designing experiment Effects of Diazepam by oral administration with water,milk, grapefruit juice,alcohol, tea Group member: Christine Tiffany Terry Homer Tutor: Professor lv, Professor Xiong www.themegallery.com
Presentation Outline • 1. Introduction 1.1 case 1.2 questions • 2. Experiment Procedure • 3. Results (Data Analyses and Statistics)aaa3.1. Sleeping latency 3.2. Sleeping duration 3.3. Open-field • 4. Conclusion www.themegallery.com
Introduction • Case ? Alcohol +hypnotics=toxin www.themegallery.com
Questions about administration of hypnotics are raised up • Why dose hypnotics with alcohol will produce toxin? • Isn’t it better to dose hypnotics with milk than with water? • Why it’s not proper to dose hypnotics with tea? • It’s reported that Grapefruit juice will sufficiently increase the hypnotic potency, true? alcohol tea www.themegallery.com
Experiment procedures www.themegallery.com
3.Results • 3.1. Sleeping latency www.themegallery.com
3.Results 3.2. Sleeping duration www.themegallery.com
3.Results Observation of mice’s action www.themegallery.com
3.Results 3.3. Open-field Water vs. alcohol Grapefruit juice, water and alcohol www.themegallery.com
4.Conclusions • (1)Oral administration with milk will lower the drug potency • (2)Oral administration with Grapefruit juice will sufficiently increase the hypnotic potency and cause adverse effect. • (3)Oral administration with tea will lower the hypnotic potency. • (4)Oral administration with alcohol will sufficiently increase the hypnotic potency and cause severe adverse effect. www.themegallery.com