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Stress and Healing

Stress and Healing. Ronald Glaser and Janice Kiecolt-Glaser Nate Cousins & Sean Harrington AP Psychology Hr. 3 May 23 nd 2007 Mr. Elmhorst. Background. Hans Selye began research on organisms’ non-specific response to stress. Most attribute Selye with General Adaptation syndrome.

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Stress and Healing

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  1. Stress and Healing Ronald Glaser and Janice Kiecolt-Glaser Nate Cousins & Sean Harrington AP Psychology Hr. 3 May 23nd 2007 Mr. Elmhorst

  2. Background • Hans Selye began research on organisms’ non-specific response to stress. • Most attribute Selye with General Adaptation syndrome. • Selye discovered and documented that stress differs from other physical responses in that stress is stressful whether the one receives good or bad news, whether the impulse is positive or negative. • He also pointed to an alarm state, a resistance state, and an exhaustion state

  3. Background (cont) • Several research studies have demonstrated that stress delays wound healing. • This study tests the relationship between marital stress and local cytokine production, which is associated with healing.

  4. Method • Participants: 42 healthy married couples • Ages: 22-77 • Married an average of 12.55 years • Materials: Blister roof- induces blisters in the forearm

  5. Method • Couples spent two 24 hour periods in a hospital research unit for a crossover trial. • During the first admission couples were subjected to positive interactions regarding their marriage. • During the second admission couples discussed marital disagreements, where stress levels were unarguably increased.

  6. Method During each encounter blisters were induced to participants’ forearms. Wound healing was assessed throughout the day, comparing the difference in healing between the positive and negative groups.

  7. Results • Couples’ blister wounds healed more slowly, and local cytokine production was also lower at wound sites following marital conflicts than after social support interactions • Couples who demonstrated consistently higher levels of hostile behaviors across both their interactions healed at 60% of the rate of low hostile couples. • High hostile couples also produced relatively larger increases in plasma interleukin-6 and tumor necrosis factor-a the morning after a conflict than after a social support interaction compared to low hostile couples.

  8. Discussion • The study furthered Selye’s research demonstrating that stress has an effect on wound healing. • Furthermore, the study demonstrated that negative stress, the marital conflict, has a greater effect on the rate of healing. • It also confirmed hypothesis on the relationship between proimmflamatory cytokine and ageing.

  9. Conclusion • The theory about stress is becoming more widely accepted. • As more research is done the physiology behind stress will become more understood. • Everyone handles stress differently, but the more stress someone experiences the more likely they are to get sick, and the less likely they will be to have a speedy recovery.

  10. Refrences • Janice, Kiecolt-Glaser. Stress and Wound Healing. 2005. 20 May. 2007. pni.psychiatry.ohio-state.edu/jkg/wound.html • "Hans Selye." McGraw-Hill Companies. 21 May 2007 <http://www.dushkin.com/connectext/psy/ch12/bio12.mhtml>. • http://biology.about.com/library/weekly/aa070998.htm

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