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Population Genetics

Population Genetics. FRSC 8104 Criminalistics II Professor Bensley. FRSC 8104 – Pop. Genetics Objectives. Comprehend the basic concepts of population genetics to include definitions of various terms.

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Population Genetics

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  1. Population Genetics FRSC 8104 Criminalistics II Professor Bensley

  2. FRSC 8104 – Pop. Genetics Objectives • Comprehend the basic concepts of population genetics to include definitions of various terms. • Apply the concepts of the Hardy-Weinburg equilibrium to systems commonly encountered in forensic serological testing. • Apply the law of independent events and Chi Square distribution to forensic serological concepts.

  3. FRSC 8104 – Pop. Genetics Outline • Introduction – Review • Definitions – Review? • Allele • Homozygous • Heterozygous • Genetics • Genotype • Phenotype • Diploid • Haploid

  4. FRSC 8104 – Pop. Genetics Outline • Meiosis

  5. FRSC 8104 – Pop. Genetics Outline • Spermatogenesis • Oogenesis • New Hypothetical System • Allelic Frequency Calculations • Phenotype Frequency Calculations • Hardy-Weinberg Equilibrium • Conditions • Assumptions • Reality • Law of Independent Events

  6. FRSC 8104 – Pop. Genetics Outline • ABO Blood Type Phenotype Frequencies • Forensic Examples • Secretors and Non-Secretors • Probability of a “Match” • Probability of Discrimination • Chi Square Distribution

  7. Chi Square Example Chi Square = .059 + .269 + .307 = 0.635 Degrees of Freedom = #phenotypes - # alleles = 3-2 =1 Use Chart of Chi Square Distribution  If your Chi Square calculated value falls below the 0.05 column the population is assumed to follow H-W principles.

  8. Chi Square Distribution Table

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