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3rd International Research Meeting June 10th, 2011, Hôtel Marigny

3rd International Research Meeting June 10th, 2011, Hôtel Marigny. Introduction Pr Jean-François Delfraissy. Institut de Microbiologie et Maladies Infectieuses (IMMI). Agence Nationale de Recherche sur le Sida et les Hépatites Virales (ANRS). CHU Bicetre – Paris XI. Pneumonia. Diarrhoea.

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3rd International Research Meeting June 10th, 2011, Hôtel Marigny

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  1. 3rd International Research MeetingJune 10th, 2011, Hôtel Marigny Introduction Pr Jean-François Delfraissy Institut de Microbiologie et Maladies Infectieuses (IMMI) Agence Nationale de Recherche sur le Sida et les Hépatites Virales (ANRS) CHU Bicetre – Paris XI

  2. Pneumonia Diarrhoea Other infections Non infectious 18% % of deaths 36% 15% 31% The Heavy Burden of Infectious Diseases Infectious diseases account for 26% of all deaths worldwide Leading cause of mortality in ressources limited countries Two-thirds of worldwide deaths in children <5 years old 2

  3. Humans Vectors Hosts « Emergence »: a global threat • Newly apparent pathogens:HIV, Ebola, H5N1, H1N1… • Rapidly increasing in incidence or geographic range :dengue,chikungunya, West Nile • Multidrug Resistant Pathogens : NDM-1, E.Coli (EHEC) • Importance of zoonosis • Multidisciplinary approach

  4. A new vision of microbiology • Discovery of new viruses, new bacteria • The commensal microbiota : from homeostasis to disease • New technologies : deep sequencing, omics… • Molecular basis of host defense • Host genetic control • Biomarkers, Point of care, Pharmacogenomics

  5. Medical and Scientific challenges • Transmission of infection (mechanisms, nosocomial…) • Emerging diseases; zoonosis, human ecology, biodiversity • Resistance : Tuberculosis, Bacteria, MDR… • Infectious agents and non infectious diseases: cancer, cardiovascular, obesity, allergy, inflammation,… • Vaccination: new vaccines, immunity, SHS… • The big 3 : HIV, Tuberculosis, Malaria

  6. IMMI: French Biomedical research Centers Institut Pasteur Paris Pitié Salpétrière Mondor/Bicêtre/Orsay/CEA/Saclay Bichat/St Louis Cochin/Cordeliers Institut Pasteur Lille Strasbourg BIOPOLE Lyon-Grenoble IRT Lyon/Pasteur Bordeaux INFECTIOPOLE SudMarseille-Montpellier-Nice IHU

  7. Microbiology and Infectious DiseasesKey points: France 2011 • Major Institutions : Institut Pasteur, Inserm, CNRS, IRD • Others : ANRS, CEA, CIRAD, INRA, INVS, Universities • 12% of French research forces: 300 teams, 2000 Scientists & Technical staff • 18% of French biomedical publications: 5000 publications per year • Translationnal and clinical research: 35 clinical units involved, including HIV and hepatits • Network of vaccine research centers • Large research network in ressources limited countries

  8. Scientific Program (1) 8.55 -11.30 • Session 1: UNDERSTANDING INFECTIOUS DISEASES: NEW MECHANISMS & PARADIGMS • Session 2: NEW TARGETS AND TOOLS IN INFECTIOLOGY 11.30 Transfer to Elysée Palace 12.15 The President Sarkozy Lecture 12.45 – 13.45 Buffet-Lunch

  9. Scientific Program (2) 14.00 – 14.30 • Session 3: NORTH-SOUTH PARTNERSHIPS: POWERFUL RESEARCH TOOLS 14.30 – 17.00 R&D Dating Session : Twenty one companies will meet successively with 4 scientific teams representatives This very short meeting allows to define whether a future in depth meeting should be scheduled in case of confirmed common interests 17.15Conclusion remarks: Pierre TEILLAC – Chairman of ARIIS 17.45Allocution by the Minister Mr Eric BESSON

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