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2/25/14 109th Day of School

2/25/14 109th Day of School. Learning goal (7 .L.2.2 & 7.L.2.3) : I will be able to describe sickle cell anemia and use a Pedigree to track inheritance of such genetic disorders. Due Today: Late work Evening Assignment: FINISH Genetic Vocabulary chart. Hawley Hornets Team Dr. Batten

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2/25/14 109th Day of School

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  1. 2/25/14109th Day of School Learning goal (7.L.2.2 & 7.L.2.3): I will be able to describe sickle cell anemia and use a Pedigree to track inheritance of such genetic disorders. Due Today: Late work Evening Assignment: FINISH Genetic Vocabulary chart

  2. Hawley Hornets Team Dr. Batten Shon B. Justice N. Logan Jacobi Cody Wilkins Ethan Batten-Hicks $200 from Hawley!!! $650 Total raised so far A way you and your family can help fund research to fight childhood cancers: Donate at least $1 dollar to the Hawley Hornets team. Homeroom teachers will collect your donations until Friday. *** all donations are tax deductible *** St. Baldrick’sCancer Research Fundraiser

  3. Read the two paragraphs from McDougall p. C147 and answer the following on the slip of paper. How is having sickle cell disease detrimental to a person’s health? How could having the sickle cell trait actually be beneficial? Why does sickle cell anemia have the highest incidence in African-American populations? McDougall p. C147 Do Now

  4. Sickle Cell Anemia http://youtu.be/2CsgXHdWqVs

  5. Description: Sickle Cell Anemia is a recessive genetic disorder caused by a mutation that deforms the hemoglobin proteins in red blood cells leading to a sickle shape. Symptoms include intense pain, fatigue, stunted growth. Cause: Sickle cell anemia is caused by a single mutation in the hemoglobin gene on chromosome 11 resulting in a change in the hemoglobin protein. Inheritance: Sickle cell anemia is a recessive disorder. Patients who carry only one allele for the sickle cell mutation (Ss) are carriers of the sickle cell trait. Only people who inherit two mutated alleles have sickle cell anemia (ss). Incidence: SCD affects 90,000 to 100,000 Americans. SCD occurs among about 1 out of every 500 Black or African-American births. SCD occurs among about 1 out of every 36,000 Hispanic-American births. SCT occurs among about 1 in 12 Blacks or African Americans. (Source: CDC) Treatment: There is no cure for sickle cell anemia however you can treat the symptoms. Pain medication, Hydroxyurea (reduces painful crisis), blood transfusions, antibiotics (to prevent infections especially in children). McDougall p. C146-147 Sickle Cell Anemia

  6. Sickle Cell Anemia Pedigree Can you write a story describing this family

  7. Create a pedigree with the following information: • Both grandmother and grandfather are carriers of the sickle cell trait. • They have four children – • Healthy male who marries a woman with the sickle cell trait. • They have a female child who is healthy • Male who has sickle cell anemia (didn’t marry or have children) • Male who is a sickle cell carrier (didn’t marry or have children) • Female who also is a sickle cell carrier and marries a man who has sickle cell anemia • They have male and female children with the sickle cell trait Sickle Cell Pedigree

  8. Create a pedigree with the following information: • Both grandmother and grandfather are carriers of the sickle cell trait. • They have four children – • Healthy male who marries a woman with the sickle cell trait. • They have a female child who is healthy • Male who has sickle cell anemia (didn’t marry or have children) • Male who is a sickle cell carrier (didn’t marry or have children) • Female who also is a sickle cell carrier and marries a man who has sickle cell anemia • They have male and female children with the sickle cell trait Sickle Cell Pedigree

  9. On the BACK On the FRONT Definition/characteristics: A trait or characteristic that is developed or learned through life. Traits you aren’t born with. Traits GENERALLY not controlled by DNA. Examples: Walking, speaking English, dyed hair, pierced ears, Glasses, skin cancer? Acquired Trait Acquired trait Inherited trait Sexual reproduction Heredity DNA Chromosome Gene Allele Genotypes Phenotype Dominant Recessive Gregor Mendel Pea Plants Huntington’s Disease Punnett Square Monohybrid cross Homozygous(Purebred) Heterozygous (Hybrid) Mutation Genetic Disorder Sickle Cell Anemia Hemoglobin Pedigree Genetics Vocabulary Flashcards due 2/28/14

  10. Make a genetics vocabulary word chart as a study guide for your vocabulary quiz on Friday. See some examples below. Include ALL 24 vocabulary words! Genetics Vocabulary Chart – Due 2/26/14

  11. Choose ONE of the following projects to do as a summative MAJOR assessment for the Genetics Unit. Do detailed, quality work to get full credit. Genetics Projects – due 3/21/14

  12. Tonight… 1. FINISH Genetics Vocabulary chart 2. Complete late work! Evening Assignment

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