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Rikkunshito (1.0%) : 25 days (n=19) *

Median survival. Control : 23 days (n=20). Rikkunshito (0.5%) : 24 days (n=20). Rikkunshito (1.0%) : 25 days (n=19) *. 100. 80. 60. Survival rate (%). 40. 20. 0. 0. 2. 4. 6. 8. 10. 12. 14. 16. 18. 20. 22. 24. 26. 28. 30. Time after treatment (days).

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Rikkunshito (1.0%) : 25 days (n=19) *

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  1. Median survival Control : 23 days (n=20) Rikkunshito (0.5%) : 24 days (n=20) Rikkunshito (1.0%) : 25 days (n=19) * 100 80 60 Survival rate (%) 40 20 0 0 2 4 6 8 10 12 14 16 18 20 22 24 26 28 30 Time after treatment (days) Supplemental Figure 6 Effect of p.o. administration of rikkunshito on survival of CT-26 colon carcinoma-bearing mice. Survival was significantly increased in CT-26 colon carcinoma-bearing mice given chow containing 1.0% rikkunshito compared to mice given control chow. * P < 0.05.

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