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The role of IRE in Nuclear Medicine The success story of a cooperation between South- Africa and Belgium

The role of IRE in Nuclear Medicine The success story of a cooperation between South- Africa and Belgium. Catherine Gernay Director IRE . Main topics. What is IRE ? Medical Isotopes for diagnosis: a global just-in-time supply chain

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The role of IRE in Nuclear Medicine The success story of a cooperation between South- Africa and Belgium

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  1. The role of IRE in NuclearMedicine The success story of a cooperationbetween South-Africa and Belgium Catherine Gernay Director IRE

  2. Main topics • What is IRE ? • Medical Isotopes for diagnosis: a global just-in-time supply chain • IRE and NTP: a long-standing and successful cooperation

  3. Main topics • What is IRE ? • Medical Isotopes for diagnosis: a global just-in-time supply chain • IRE and NTP: a long-standing and successful cooperation

  4. Belgium: a global actor in nuclear medicine

  5. Welcome to Belgium ! • Strategic location for logistics • Transport • Road network • 4 int’l airports < 350km • Research Reactors • 3 reactors < 300km • 1 reactor < 1000km • Other companies on our site: • Cyclotron isotope production • Gamma sterilization • Transport

  6. Presentation of IRE A short movie introduction …

  7. National Institute for Radioelements • 150 employees • Turnover M€ 45 • Mission • Contribute to public health • Production of radionuclides for nuclear medicine • Minimum impact on its workers, local residents and the environment • Environmental monitoring • Measurement and monitoring of radionuclides • Management of radioactive waste • Consultancy projects to improve nuclear safety

  8. Innovation • Modernization of production facilities • Continuous safety improvement • Construction of the new plant which will process LEU targets

  9. A subsidiary of IRE and SFPI Created July 1st 2010 25 employees 2 main activities Radiopharmaceuticals production Services related to environmental monitoring Recent developments: Partnership in China, Clinical study initiated on pain palliation (Bone Cancer) in Shanghai IRE-ELiT Environment & Lifescience Technology

  10. Main topics • What is IRE ? • Medical Isotopes for diagnosis: a global just-in-time supply chain • IRE and NTP: a long-standing and successful cooperation

  11. Main fields of application of nuclear medicine Images courtesy Prof. R. Baum, Bad Berka (Germany)

  12. Diagnostic applications

  13. The manufacture of Tc-m99 (SPECT)80% of the imaging procedures worldwide A Just-in-time process … Generator99Mo/99mTc 99MoLiquid 235UTargets Generator manufacturer RadioPharmacy / Hospital Reactor Processing

  14. Five reactors provide over 90% of the main radioisotopes worldwide HFR 1966 NRU 1957 BR2 1961 LVR-15 1957 OSIRIS 1966 OPAL 2008 SAFARI 1965 Reactors: NRU (CAN), HFR (NL), BR2 (BE), Safari (SA), Osiris (FR), OPAL (AUS) Processors: MDS-Nordion (CAN), IRE (BE), Covidien (NL), NTP (SA), ARI (AUS) Generators: LMI (US), MallinckrodtNL & US, GE (GB), IBA (FR), NTP (SA), ANSTO (AUS), FUJI RI & NMP (JPN), CIC (China), …

  15. International cooperation is crucial to ensure security of supply BR2 1961 Reactors: NRU (CAN), HFR (NL), BR2 (BE), Safari (SA), Osiris (FR), OPAL (AUS) Processors: Nordion(CAN), IRE (BE), Covidien (NL), NTP (SA), Ansto(AUS) Generators: LMI (US), Covidien NL & US, GE (GB), IBA (FR), NTP (SA), Ansto(AUS), FUJI RI & NMP (JPN), CIC (China), Monrol (Tu), Ipen (BRA)

  16. Main topics • What is IRE ? • Medical Isotopes for diagnosis: a global just-in-time supply chain • IRE and NTP: a long-standing and successful cooperation

  17. IRE and NTP :A long-standing and successful relationship • A historical relation initiated by IRE in the 90s • Two partners of similar sizes, backing each other up on the main radio-isotopes • Similar business cultures focused on patient safety and security of supply • The IRE-NTP consortium meets ca. 50% of the world demand in medical radioisotopes • In shortage times, we ramp up to 70% of the world market • >> a highly valued cooperation by the nuclear medicine community on 5 continents !!

  18. Thank you for your attention

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