Imatinib mesylate tablets

1. Imatinib mesylate tablets Overview Imarech is a formulation of imatinib mesylate tablet. It is used in the treatment of cancers like acute lymphoblastic leukemia. This medicine is used to treat tumors that are Philadelphia chromosome-positive.

2. Pharmacodynamics Imatinib is an antineoplastic agent and a protein-tyrosine kinase inhibitor that inhibits the BCR-ABL tyrosine kinase, and it works as a specific inhibitor of several tyrosine kinase enzymes. Chronic myelogenous leukemia is associated with the Philadelphia chromosome promoting the generation of BCR-ABL (mutation, which results from the combination of two genes, known as BCR and ABL). BCR-ABL generates a fusion protein that acts as a constitutively active tyrosine kinase and imatinib works to inhibit this constitutive enzymatic activity. Usage Imarech (Imatinib mesylate) is used to treat certain types of cancers of blood cells and it works by preventing the multiplication and division of cancer cells. Do not perform activities that require attention and concentration, and get plenty of rest during the course of this medication to avoid side effects like dizziness and drowsiness. Dosage may vary differently to the patients according to their age, weight, and other health concerns. Do not discontinue the dosage of Imarech tablets without consulting with your healthcare professional.