1 / 2

Animal Studies for ADC

Pharmacological studies in various animal models play a crucial role in early-stage ADC development, and afford predictions of therapeutic and safety parameters for subsequent human trials.<br>

CreativeBiolabs
Télécharger la présentation

Animal Studies for ADC

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Animal Studies for ADC Emerging Needs for Animal Studies Pharmacological studies in various animal modelsplay a crucial role in early-stage ADC development, and afford predictions of therapeutic and safety parameters for subsequent human trials. However, these studies usually involve the compliance of sophisticated regulationsand can only be conducted by certifi-cated institutes, which could be an impediment for smaller companies. Oftentimes, drug candidates with promising results from in vitro and cell-based experiments suffer from unexpected failure in animal models. Thus, for early-stage drug development, it is always advisable to “fail fast and fail cheap”. Animal Studies Can Be Affordable AtCreative Biolabs, we are devoted to offerlow-cost animal models for pre-clinical drug development. Together with our partner labs, weprovide animal studies to conductpreliminary evaluation of ADMET properties and biological efficacy of drug candidates. The tentative nature of our services intends to offer budget options especially for researchers from startup companies and research institutes where cost is often the primary concern. Customers choosing our services can usually experience a saving of up to 50%. Our Capability We are specialized in exploratory non-GLP animal studies in toxicity, and pharmacoki- netics and drug efficacy (Figure 1) using a wide range of animal models including Farm animals (swine, sheep, goat) Dogs Rabbits Ferrets Non-human primates Rodents

  2. Our expertise includes infectious diseases, oncology, dermatology, inflammation, autoimmunity and metabolic disorders.All service packages include a detailed experimental record and a data analysis report written by our seasoned scientists, to bring you maximum confidence in future GLP- level experi-ments and human studies. Figure 1. Evaluation of a novel anticancer agent in mice: MicroSPECT/CT imaging of tumor-bearing mice (left); tumor to muscle ratio calculated from MicroSPECT/CT imaging (right). Your study depends on getting the right services exactly when you need them, without delays or interruptions, and more importantly, at the right price. Rely on our well-established global network and advanced facilities, your demands will always be fulfilled in a timely manner. With a large breadth of collaboration with research institutes and commercial suppliers, our services are ready to get started as soon as you are. Featured Cancer Cells Lines for Xenograft Models Cell lines Species Cancer type HeLa Homo sapiens Cervix adenocarcinoma MCF-7 Homo sapiens Breast adenocarcinoma U87MG Homo sapiens Glioblastoma-astrocytoma HT-29 Homo sapiens Colon adenocarcinoma A549 Homo sapiens Lung carcinoma HEP-G2 Homo sapiens Hepatocellular carcinoma K-562 Homo sapiens Chronic myeloid leukaemia PC3 Homo sapiens Prostate adenocarcinoma A375 Homo sapiens Malignant melanoma USA Europe 45-1 Ramsey Road, Shirley, NY 11967, USA Tel: 1-631-871-5806 Fax: 1-631-207-8356 Email: info@creative-biolabs.com Ringstrasse 4, 64401 Gross-Bieberau, Germany Tel: 44-207-097-1828

More Related