Lenalidomide |LENALID 5MG,10MG,15MG,25MG|Blueberry pharmaceuticals

1. Lenalidomide |LENALID 5MG,10MG,15MG,25MG|Blueberry pharmaceuticals LENALID 5MG,10MG,15MG,25MG: Lenalid 5mg,10mg,15mg,25mg contains Lenalidomide as an active substance which belongs to thalidomide analogue. Lenalid 5mg,10mg,15mg,25mg contains some pharmacological activities like immuno modulatory, anti- neoplastic, & anti- angiogenesis. Lenalid 5mg,10mg,15mg,25mg is a prescription medicine; used under the supervision of medical oncologist. Lenalid 5mg,10mg,15mg,25mg is used by combining with dexamethasone. LENALID INDICATION : The most common indications of Lenalid 5mg,10mg,15mg,25mg are; Multiple myeloma: Lenalid 5mg should be used in combination with dexamethasone. Myelodysplastic syndrome: Lenalid 5mg,10mg,15mg,25mg is used to treat this condition Mantle cell lymphoma: Lenalid 5mg,10mg,15mg,25mg is used for this condition, if patients are not responding to the Bortezomib treatment.

2. LENALID 5MG,10MG,15MG,25MG LENALID MECHANISM : Lenalid 5mg,10mg,15mg,25mg includes in the restraint of tumor rot factor alpha arrangement, which support the T-cells and causes lessening serum levels of cytokines vascular endothelial development factor and fundamental fibroblast development factor. Lenalid 5mg,10mg,15mg,25mg is additionally engaged with the preclusion of angiogenesis. Lenalidomide is additionally empowered G1 cell cycle capture and apoptosis of ruinous cells. LENALID DOSAGE & ADMINISTRATION The usual prescribed dose of Lenalidomide in myelodysplastic syndromes is 10mg should be given as once a day. For renal damaged patients; In Patients with CrCl>60ml/min should not require dosage adjustment of Lenalidomide. In Patients with CrCl 30 to 60ml/min, 5mg of Lenalidomideshould be given orally as once a day.

3. In Patient with CrCl <30ml/min, 2.5mg of Lenalidomideshould be administered orally as a once a day. DOSAGE VARIATION THROMBOCYTOPENIA Drops to <50000/mcL, therapy should be interrupted. Back to > or equal to 50000/mcL, continue the Lenalidomideof 5mg/day. NEUTROPENIA Drops to <500/mcL, therapy should be postponed. Back to > or equal to 500/mcL, treatment should be continue to 5mg/day. MULTIPLE MYELOMA In this condition, Lenalidomide is concomitant with dexamethasone. The usual dose of Lenalidomide is 25mg should be administered as once daily on day 1 to 21. The dose of dexamethasone; 40mg of dexamethasone should be followed on day 1 to 4, 9 to 12 & 17 to 20 of each 28 day cycles. Patient with >75 years, 20mg of dexamethasone should be recommended on day 1, 8, 15, & 22. MANTLE CELL LYMPHOMA The advised dose of Lenalidomidefor this condition is 25mg should be administered orally as once daily. For renal damaged patients Patient with CrCl 30 to 60ml/min, 10mg of Lenalidomideshould be administered Patient with CrCl<30ml/min, 15mg of Lenalidomideshould be used for q48hr. as once daily.

4. Pediatrics The potency & effectiveness of Lenalidomide has not been evaluated in pediatric patients with age of <18 years. LENALID 5MG,10MG,15MG,25MG SIDE EFFECTS Second primary malignancies, Liver toxicity, Hypersensitivity reactions, Tumor lysis syndrome, Tumor flare reactions, Thyroid disorders, Fetal toxicity, Hematological toxicity, Elevation of mortality rate COMMON SIDE EFFECTS Fatigue, Asthenia, Pyrexia, Diabetes mellitus, Rash, Insomnia, Depression, Deep vein thrombosis, Myocardial infraction, Renal failure, Squamous cell carcinoma, Basal cell carcinoma, Pain, Diarrhea, Dyspepsia, Bone pain, Neck pain, Muscle weakness, pain, Respiratory infections, UTI, Influenza, Sepsis, Headache, Anemia, Loss of appetite, Hypokalemia, Hyperglycemia, Hypocalcaemia, Dehydration, Gout CONTACTS Phone :91-97890 77748 Email: blueberrypharmacy@gmail.com WEBSITE: https://blueberrypharma.com/lenalidomide.php