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Genacol

Genacol is a safe substance that supplies the necessary elements in order to nutritionally support the body’s production of collagen

Genacol
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Genacol

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  1. Why choose AminoLock® Collagen has the lowest molecular size peptides in the world, at less than 1 kDa providing the benefit of superior bioavailability and proven effectiveness for joint health* Other standard collagen brands It’s not how much you take... 3 6 1 3 to 5 kDa PER DAY PER DAY VS kDa it’s how much you absorb! Smaller molecule = Superior Absorption Bigger molecule = Lower Absorption Better results! Genacol® continuously invests in scientific research to improve the health benefits of our products. As a dominant player in the industry, we believe it’s important to continually surpass ourselves so we can offer the best products available on the market. Genacol®’s proprietary Aminolock® Sequence Technology, the result of many years of research, helps improve absorption and thereby maximizes the beneficial effects*. What is Collagen ? Collagen is the fibrous structural protein that makes up the white fibres of joints, skin, tendons, bones, cartilage and all other connectives tissues. The production of collagen in the body slows down insidiously with age. The proof of the effectiveness in using Genacol®’s unique Very Low Molecular Weight AminoLock® Collagen is now patent pending in the USA (Application number 62/426,908) and Canada (Application number 017808-0005). Genacol is a safe substance that supplies the necessary elements in order to nutritionally support the body’s production of collagen. It helps to: • Maintain healthy joints* Genacol® ensures you to find: • Relieve joint discomfort* • • • • Proven effectiveness, supported by three published clinical studies Products to support joint, cartilage and bone health and help sleep* Smaller dosage requirements compared to other brands Highest quality of Collagen on the market - winner of 6 consecutive Consumer’s Choice Award. • Protect against cartilage deterioration and joint tissue degeneration* • Improve mobility and flexibility of joints* Try it and feel the difference ! *These statements have not been evaluated by the Food and Drug Administration This product is not intended to diagnose, treat, cure or prevent any disease.

  2. Reliability The proof is in third party testing Patent-Pending Technology The proof of the effectiveness in using Genacol®’s unique very low molecular weight AminoLock® Collagen is now patent pending. NON-GMO Our products are NON-GMO certified. Dr. Haddad, PhD Scientific Consultant and Phamacologist Genacol® continually invest in research that demonstrates the benefits of our joint supplements. Three published and internationally recognized clinical studies have provided scientific confirmation that Genacol® helps to maintain healthy joints. These clinical studies can be fully reviewed on our website (genacol.com). #1 Absorbable form of Collagen AminoLock® Collagen has the lowest molecular weight in the world, allowing superior bioavailability*. BRUYERE study Supported by 3 clinical studies The effectiveness of AminoLock® Collagen for joint health* is supported by three published and internationally recognized clinical studies. The first study was conducted over a six-month period at the University of Liege and included 200 subjects, aged 50 and over, who suffered from joint discomfort. The objective of the study was to demonstrate the efficacy of AminoLock® Collagen (1200 mg) in maintaining healthy joint*, as compared to a placebo. Collagen made in USA Genacol®’s AminoLock® Collagen is produced in Sunflower, Mississippi, USA. PARM study The second study was conducted at Veterans Memorial Medical Centre in the Philippines. Gluten-free Our products do not contain any gluten. The objective of the study was to demonstrate the efficacy of AminoLock® Collagen in maintaining healthy joint*, as compared to a nonsteroidal anti-inflammatory drug. The study was conducted over a six-month period and included 113 patients. Pasture-raised The cattle used to produce our collagen are pasture-raised and grass-fed. SUAREZ study The third clinical study was conducted at the University of Santo Tomas Hospital in the Philippines. Available worldwide Our products are sold in more than 40 countries, making Genacol® the #1 collagen brand for joint health in the world! The objective of the study was to determine the efficacy of AminoLock® Collagen, combined with physical exercise, in helping to maintain healthy joint*. The placebo-controlled, triple-blind study included 109 subjects, aged 50 and older, who had experienced knee discomfort for over a month. cGMP certified Our products are made in an FDA regulated plant that is cGMP and HACCP certified. Recently, ConsumerLab.com, an independent organization that evaluates nutritional products in the USA, recognized Genacol®’s clinical study as: ONE OF THE LARGEST STUDIES ABOUT COLLAGEN HYDROLYSATE. *These statements have not been evaluated by the Food and Drug Administration This product is not intended to diagnose, treat, cure or prevent any disease.

  3. The liquid solution for joints! Original Formula since 2000! Original Li- quid Fast absorbing liquid formula! Helps to maintain healthy joints* LIQUID FORMULA CAPSULES AminoLock® Collagen Helps to maintain healthy joints* Genacol®Original is made with 100% AminoLock® Collagen using a unique technology that minimizes collagen’s molecular weight to less than 1 kDa to maximize absorption by the body. Genacol®Original protects against cartilage deterioration and supplies the amino acids contributing to the formation of cartilage. It also helps maintain supple and flexible joints, and relieves joint discomfort and stiffness. Genacol®Original Liquid Formula is designed and formulated to maintain joint health in a natural way, and has the added benefit of fighting “pill fatigue.” Easy to use, this product is ideal for people with an active lifestyle. Faster absorption: the body more quickly absorbs the liquid formula. Genacol®Original Liquid Formula is made with 100% AminoLock® Collagen using a unique technology that minimizes collagen’s molecular weight to less than 1 kDa to maximize absorption by the body. Further to meeting the industry’s highest manufacturing standards, AminoLock® Collagen has no adverse effects, is GMO-free, and comes from pasture-raised animals. Supplement Facts Serving Size 3 capsules Servings Per Container 30 Supplement Facts Serving Size 15 mL Servings Per Container 30 Amount Per Serving 5 2 g % Daily Value** Calories Protein Amount Per Serving % Daily Value** Dosage (adult): Pour 15 ml in the measuring cup and mix with water or juice, once daily. 4% Calories Protein 5 Dosage (adult): Take 3 capsules once daily, ideally at bedtime, or as directed by your health care practitioner. Hydrolyzed collagen from bovine (1) source 2 g 4% 1200 mg † Hydrolyzed collagen from bovine (1) source ORIGINAL ** Percent Daily Values are based on a 2000 calorie diet. † Daily Value not established. ORIGINAL 1200 mg † ** Percent Daily Values are based on a 2000 calorie diet. † Daily Value not established. (1) Pasture-raised Other ingredients: gelatin, vegetable magnesium stearate. (1) Pasture-raised Other ingredients: purifed water, erythritol, citric acid, green apple favor, sodium benzoate, potassium sorbate, stevia. 90 capsules and 180 capsules bottles available! *These statements have not been evaluated by the Food and Drug Administration This product is not intended to diagnose, treat, cure or prevent any disease.

  4. The most complete joint formula available! The best combination! Original Li- quid Helps to maintain healthy joints* Helps lubricate and protect joints* LIQUID FORMULA CAPSULES Helps to maintain healthy joints* Helps lubricate and protect joints* Genacol®Optimum is one of the most complete joint formula available. AminoLock® Collagen, Glucosamine, Chondroitin, and MSM are essential ingredients to maintain joint health. Impressive joint health results are achieved because of the combination of the 4 natural active ingredients. Genacol®Plus is a product specifically designed for joint health. The collagen-glucosamine combination is the winning formula when it comes to ensuring good joint function and health. Combined with glucosamine, which helps lubricate and protect joints, Genacol®Plus made with AminoLock® Collagen is the perfect 2-in-1 product, and provides excellent value for money. Genacol®Optimum’s liquid form facilitates its absorption by the body, helps fight «pill fatigue», and is ideal for people who wish to live an active lifestyle while maintaining and preserving optimal joint health. Genacol® Optimum supports healthier and stronger ligaments and tendons and promotes healthy joints and connective tissues. Supplement Facts Supplement Facts Serving Size 3 capsules Servings Per Container 30 Serving Size 15 mL Servings Per Container 30 Genacol®Plus helps maintain supple and flexible joints, and relieves joint discomfort and stiffness. Amount Per Serving 5 2 g % Daily Value** Amount Per Serving 15 2 g % Daily Value** Calories Protein Calories Protein 4% 4% Dosage (adult): Take 3 capsules once daily, ideally at bedtime, or as directed by your health care practitioner. Hydrolyzed collagen from bovine (1) source Glucosamine sulfate (Crab and shrimp exoskeleton) 1500 mg † Chondroitin sulfate Hydrolyzed collagen from bovine (1) source Glucosamine hydrochloride (Crab and shrimp exoskeleton) 1500 mg † 1200 mg † 1200 mg † Dosage (adult): Pour 15 ml in the measuring cup and mix with water or juice, once daily. OPTIMUM 500 mg † ** Percent Daily Values are based on a 2000 calorie diet. † Daily Value not established. MSM (methylsulfonylmethane) 400 mg † PLUS (1) Pasture-raised Other ingredients: gelatin, vegetable magnesium stearate. ** Percent Daily Values are based on a 2000 calorie diet. † Daily Value not established. (1) Pasture-raised Other ingredients *These statements have not been evaluated by the Food and Drug Administration This product is not intended to diagnose, treat, cure or prevent any disease.

  5. The most complete formula on the market! Sleep better, move better! Original Li- quid Helps to maintain healthy joints* Helps to increase duration of sleep for occasional sleeplessness* CAPSULES CAPSULES Supports bone strength* Helps to maintain healthy joints* Genacol®Sleep & Joints is a unique combination of AminoLock® Collagen and melatonin (the body’s sleep hormone), which is largely responsible for the quality and duration of sleep. Genacol®Sleep & Joints is a natural sleep aid, does not create dependence or grogginess upon waking, do not procure any undesirable side effects and is 100% drug free. It can greatly help people who occasionally suffer from occasional sleeplessness. This innovative product is made up of a unique blend of several nutrients and vitamins to maintain strong bones and healthy joints. Genacol®Bone & Joint’s exclusive formula contains Boron and 1000 IU of Vitamin D3 to optimize the absorption of calcium also present in the capsules (600 mg / daily dosage). Genacol®Bone & Joint also contains AminoLock® Collagen, which maintain supple and flexible joints, and relieves joint discomfort and stiffness. Supplement Facts Supplement Facts Serving Size 3 capsules Servings Per Container 30 Genacol®Sleep & Joints has been specifically designed to promote a more restful night’s sleep while improving joint health. Serving Size 3 capsules Servings Per Container 30 Amount Per Serving % Daily Value** Amount Per Serving 5 2 g % Daily Value** Calories Protein 5 Calories Protein With Genacol®Bone & Joint you have a powerful nutritionnal support for bone and joint health. 2 g 4% 4% Dosage (adult): Take 3 capsules once daily at bedtime, or as directed by your health care practitioner. Hydrolyzed collagen from bovine(1) source Boron Calcium (elemental) Vitamin D3 Magnesium Manganese Vitamin K1 Zinc Copper 1200 mg 250 mcg 600 mg 1000 IU 50 mg 1.8 mg 20 mcg 7.5 mg 1 mg † † Hydrolyzed collagen from bovine (1) source Melatonin 1200 mg 9 mg † † 60% 250% 13% 90% 25% 50% 50% Dosage (adult): Take 3 capsules once daily or as directed by your health care practitioner. SLEEP&JOINTS ** Percent Daily Values are based on a 2000 calorie diet. † Daily Value not established. BONE &JOINT (1) Pasture-raised Other ingredients: gelatin, vegetable magnesium stearate. ** Percent Daily Values are based on a 2000 calorie diet. † Daily Value not established. (1) Pasture-raised Ingredients: Hydrolyzed collagen from bovine (1) source, calcium carbonate, cholecalciferol (Vitamin D3), phytonadione (Vitamin K1), magnesium oxide, zinc oxide, copper sulfate, manganese sulfate, boron citrate, vegetable magnesium stearate, gelatin. *These statements have not been evaluated by the Food and Drug Administration This product is not intended to diagnose, treat, cure or prevent any disease.

  6. What About Collagen? What is Collagen? What is the Importance of Collagen in the Body? Collagen is a hard, insoluble, and fibrous protein that makes up one- third of the protein in the human body. It is composed by a high level of the key amino acids : glycine, proline and hydroxyproline. These represent around 50% of the total amino acid content of collagen. Collagen is part of the natural composition of skin, tendons, bones, cartilage, and all other connective tissues. Collagen also gives to different organs and tissues their strength and elastic properties. 1 3 COLLAGEN DISTRIBUTION IN THE BODY (by weight ratio of dry mass) Collagen structure is a triple helix of alpha-chains of 19 amino acids. 75% Skin Non essential amino acids Proline / Hydroxyproline 6% Muscles 12% 25% Other essential amino acids 30% Bones 16% 80% Ligaments 8% 20% 67% Cartilage Alanine 90% Tendons 8% Glycine 11% Arginine Glutamic Acid This structural proteins plays a fundamental role in holding the body together. It constitutes most of the body’s structural support and is the primary substance of connective tissues. Collagen, together with elastin and glycoproteins, is responsible for the cohesion of tissues and organs. It also gives these tissues and organs hydration, resistance, elasticity and flexibility properties. It is also found widespread in the gelatinous substances of the body to provide stiffening properties, such as in the vitreous humour of the eye. Twenty-five percent of the protein weight in the human body and seventy-five percent of our skin are made of collagen. In other words, collagen is this fibrous connective tissue that holds our body together and is acting as the “glue of the body”. Besides its numerous structural properties, collagen serves as well as a main catalyst for growth and it repairs almost all the tissues of the body. *These statements have not been evaluated by the Food and Drug Administration This product is not intended to diagnose, treat, cure or prevent any disease.

  7. Collagen in Joint Structure Collagen in Joint Structure Effects of Collagen Reduction on Joints Joints exist wherever two bones meet. They play a key role to ensure smooth and safe movements between the bones involved. Joints must thus deal with two major forces, namely load (including shock absorption) and friction. Synovial fluid present in the joint space acts as a hydraulic cushion in this context. Collagen decrease affect all our body tissues and organs. This phenomenon creates, in joint structure, a reduction of functions and a loss of resistance, elasticity and flexibility. This generates, in the short or medium term, a series of reactions that for most of us emerge as follows: Percentage of collagen in joint structure • Joint discomfort or stiffness • Cartilage deterioration • Joint tissue degeneration • Ligaments and tendons weakness of injuries Joints are mainly composed of : 67% Cartilage • Muscle and Bones • Articular Cartilage • Tendons • Ligaments • Synovial Membrane and Fluid What are the benefits of Genacol® AminoLock® Collagen? In order to reduce the effects of collagen decrease, providing hydrolyzed collagen supplements to your body is the key. It has been acknowledged that Genacol® AminoLock® Collagen supplies amino acids that contribute to the maintenance of collagen in the body. Moreover, three independent studies have provided scientific confirmation that Genacol® AminoLock® Collagen helps to maintain healthy joints in a safe and natural way. It helps to: Theses different parts of the joint are mainly composed of collagen. 90% Tendons 80% Ligaments Collagen Decrease When there is a decrease of collagen production in the body, everything is affected. Weakness, overall lack of energy, stiffness and discomfort are the main symptoms of a collagen decrease. In addition, all these symptoms increase with aging. • Relieve joint discomfort* • Protect against cartilage deterioration* • Preserve joint tissue from degeneration* • Improve mobility and flexibility of joints* In fact, collagen production begins to decline as early as age 30 and this reduction becomes much more prominent from age 50 and onwards. Which Collagen Type (I – II – III – IV - V) is Genacol® AminoLock® Collagen? Even more ironically, in our early thirties, most of us accept to live with most of these minors discomforts. However, as far as the reduction of collagen in our body is concerned, these problems are just the tip of the iceberg; as they announce, together with aging, direct effects on our health and quality of life. When it comes to collagen supplement, it is not the type or source of collagen hydrolysate that is important. It is the combination of the molecular weight (for bioavailability and absorption) and the specific mix of enzymes used in the production process in order to obtain a specific amino acid profile that matter. *These statements have not been evaluated by the Food and Drug Administration This product is not intended to diagnose, treat, cure or prevent any disease.

  8. Genacol® AminoLock® Collagen Difference Why is Genacol® AminoLock® Collagen Different? Unique manufacturing process The molecular weight profile of the collagen hydrolysate is dependent on the raw materials and especially the manufacturing process used. The lowest molecular weight you have, the superior absorption by the body you will obtain. As molecular weight directly impact bioavailability, Genacol® has developed an exclusive and optimal preparation of hydrolyzed collagen called the AminoLock® Sequence Technology. Depending on the chosen enzymatic hydrolysis, which is unique to our AminoLock® Sequence Technology, a collagen hydrolysate with a molecular weight within a specified range can be obtained. The average size of commercially available hydrolyzed collagen generally varies between 6 and 10 kDa. In contrast, thanks to the AminoLock® Sequence Technology, the controlled enzymatic hydrolysis process produces peptide fragments of more uniform size which are smaller than 1 kDa. Moreover, this technology enables Genacol® to ensure its AminoLock® Collagen contains well-established proportions of key amino acids required to promote collagen production in the body and to give an optimal outcome. The processes involved in processing Genacol®AminoLock® Collagen are first demineralization, extraction of collagen to gelatine, enzymatic hydrolysis to obtain hydrolysed collagen by hydrolysis of peptide bonds of the gelatine molecules, ion exchange, filtration (such as membrane filtration technique), evaporation, sterilization and finally drying. COLLAGEN ENZYMATIC HYDROLYSIS HYDRO (H20) – LYSE (BREAK, CUT) In fact, it would take up to 5 to 10 times more of a standard hydrolyzed collagen product to obtain an equivalent concentration of certain amino acids and peptide fragments present inGenacol® AminoLock® Collagen. Medical grade laboratories In order to achieve the desired result, a specific mix of enzymes is sequentially used (AminoLock® Sequence Technology). The entire manufacturing process and quality control criteria respect the most rigorous standards in the industry. Our products are manufactured under medical grades according to the highest biotech standards and comply with all government requirements, which are regulated by the FDA and GMP and HACCP certified. Native Collagen (bovine source) Enzymatic Hydrolysis Fragments of 5 to 30 amino acids (polypeptides) The choice and order of application of the chosen enzymes, together with reaction duration, pH and temperature will allow to obtain a specific collagen hydrolysate called Genacol®AminoLock® Collagen. The molecular weight distribution is then verified and determined on each production lot by such as means of gel permeation chromatographyIn. The molecular weight distribution lower than 1 kilodalton (kDa) is Genacol® AminoLock® Collagen hydrolysate. The stainless steel equipment and self-contained CIP (Clean In Process) system ensure our products cleanliness and traceability. This entire process assure that we can offer a high-quality, reliable and efficient products to our customers. *These statements have not been evaluated by the Food and Drug Administration This product is not intended to diagnose, treat, cure or prevent any disease.

  9. About us... Afamilystory... Mission Our mission is to offer all men and women concerned about their joint health the best innovative products in terms of safety, quality and efficiency. Our three clinical studies, along with our patent pending technology, prove that our products are unique, innovative, different and efficient. Responding to our customers’ needs is our passion and continuous commitment. We are dedicated to the well-being of our customers through their joint health and healthy aging. Our credo: To achieve excellence in harmony. Guy Michaud, Genacol®’s founder, is the architect behind the best collagen for joint health on the market! In the mid-1990s, a research and development company located in Montreal discovered the virtues of collagen hydrolysate as a natural supplement to improve joint health. In October 2000, Genacol® Original Formula, made of 100% Genacol®’s AminoLock® Collagen was launched.Very quickly, this innovative product was an indisputable success because of it’s effective results on joint health. It became only a few years later a leader of its category. Over the years, Genacol® was recipient of several important awards such as the “Entrepreneur of the Year Ernst and Young” award in the “Health and Science” category and has also received the first position in health in the magazine Profit 100 for its progress between 2004 and 2009. Genacol®, proud leader in its field for more than 17 years, continues to innovate, with the goal of offering its customers effective, new products. With three independent scientific studies demonstrating the beneficial effects of its proprietary AminoLock® Collagen, Genacol® filed a patent application in Canada and the United States in early 2017. Although their products are now available in over 40 countries, Genacol® remains a human-size family owned company dedicated to the well-being of customers through their joint health. With Martin Vidal, President and Chief Executive Officer and Guy Michaud’s sons now leading the company, they now focuses on the international market, research and development of new innovative natural health products, making Genacol®the number one collagen brand for joint health company in the world!

  10. Your Genacol® products retailer: Genacol International Corporation Inc. Toll free: 1-888-514-3622 • info@genacolusa.com genacol.com

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