Graduate student of Dr. Don Bergstrom investigates the Medicinal and Bioorganic Chemistry of Nucleic Acids.

Feb 20, 2011

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Graduate student of Dr. Don Bergstrom investigates the Medicinal and Bioorganic Chemistry of Nucleic Acids. .

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Graduate student of Dr. Don Bergstrom investigates the Medicinal and Bioorganic Chemistry of Nucleic Acids.

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Graduate student of Dr. Don Bergstrom investigates the Medicinal and Bioorganic Chemistry of Nucleic Acids.

Principles of Bioorganic Medicinal Chemistry Drugs & Medicinal Chemist

Principles of Bioorganic Medicinal Chemistry Drugs & Medicinal Chemist . Lovastatin-Mevacor. August 26/2002. Zbigniew J. Witczak, Ph.D. Principles of Bioorganic & Medicinal Chemistry PHA 598A: Dr. Zbigniew J. Witczak. Learning Objectives

1.1k views • 31 slides

Isolation of Nucleic Acids

High MW Genomic DNA Isolation. Typical ProcedureCell Lysis0.5% SDS proteinase K (55o several hours)Phenol Extractiongentle rocking several hoursEthanol PrecipitationRNAse followed by proteinase KRepeat phenol extrac-tion and EtOH ppt. Phenol Extractionmix sample with equal volume of sat. p

398 views • 22 slides

Metabolism of nucleic acids

Metabolism of nucleic acids. the structure & function. The structure of nucleic acids. 1. summarize. the discovery The function The headway. A. nucleotides. base （ purine、pyrimdine ）+ ribose （ deoxyribos N-glycosyl linkage nucleoside+phosphate

1.07k views • 72 slides

Nucleic Acids: DNA, RNA and chemistry

Nucleic Acids: DNA, RNA and chemistry. Andy Howard Introductory Biochemistry 7 October 2010. DNA & RNA structure & function. DNA and RNA are dynamic molecules, but understanding their structural realities helps us understand how they work. DNA structure Characterizations B, A, and Z-DNA

693 views • 49 slides

Principles of Bioorganic Medicinal Chemistry Why Should Drugs Work?/ Biological Membranes

Unsaturated Fatty Acids. Principles of Bioorganic Medicinal Chemistry Why Should Drugs Work?/ Biological Membranes . L-phenylalanine . Zbigniew J. Witczak, Ph.D. August 29/2002. The Drug Design Process. Structural Biologist. Molecular Biologist. Org.Med. Chemist. Molecular

296 views • 11 slides

Structure of Nucleic Acids

Structure of Nucleic Acids. Lesson 1. Learning Objectives. By the end of the lesson you will:- be able to describe the structure of a nucleotide. understand how nucleotides join together to form polynucleotide chains. be able to describe, with the aid of diagrams, the structure of DNA.

260 views • 13 slides

Isolation of Nucleic Acids

Isolation of Nucleic Acids. Goals : removal of proteins DNA vs RNA isolation of a specific type of DNA (or RNA). Types of Methods : differential solubility ‘adsorption’ methods density gradient centrifugation. Types of DNA : genomic (chromosomal) organellar (satellite)

876 views • 22 slides

3. Nucleic Acids – the acids of life

3. Nucleic Acids – the acids of life. Molecules vital for life Found in the nucleus of cells Contain genetic information Deoxyribonucleic acid (DNA) Ribonucleic Acid (RNA) Monomers are nucleotides Four bases: Adenine (A), thymine (T), cytosine (C), Guanine (G).

201 views • 2 slides

Nucleic Acids: RNA and chemistry

Nucleic Acids: RNA and chemistry. Andy Howard Introductory Biochemistry 13 October 2009. RNA: structure & types mRNA tRNA rRNA Small RNAs. DNA & RNA Hydrolysis alkaline RNA, DNA nucleases Restriction enzymes DNA & RNA dynamics and density measurements. What we’ll discuss.

599 views • 47 slides

AMPLIFICATION OF NUCLEIC ACIDS

AMPLIFICATION OF NUCLEIC ACIDS. By. Dr. Emad AbdElhameed Morad. Lecturer of Medical Microbiology and Immunology. Amplification. In vivo (inside a cell). In vitro (In a reaction tube). Genetic recombination. Target amplification (PCR-based methods). Signal amplification. Hot start PCR.

456 views • 17 slides

Hybridization of Nucleic Acids

Hybridization of Nucleic Acids. DNA1. DNA2. RNA. Probe. Northern hybridization. Southern hybridization. Juang RH (2004) BCbasics. Preparation of Traditional Nucleic Acid Probe. Amino acid sequence. GLY-ASP-GLU-SER-SER-VAL-LEU-----. GGG-GAC-GAG-TCC-TCC-GTT-CTC---.

846 views • 44 slides

Metabolism of nucleic acids

Metabolism of nucleic acids. Nucleoprotein in foods. protein. nucleotides. Ribonuclease(deoxyribonuclease). nucleotidases. nucleosidases. Bases pentoses phosphates. reused. catabolism. reused. 1. biosynthesis of purine nucleotides.

1.01k views • 49 slides

The biochemistry of nucleic acids

The biochemistry of nucleic acids. Tommer Ravid Room 1-523 Tel: 658 4349 e-mail: travid@cc.huji.ac.il. Metabolism of nucleic acids (DNA and RNA) 1. In many cases requires proofreading. 2. In many cases requires a plan (template) in addition to substrates.

1.25k views • 103 slides

Biological and Bioorganic Chemistry

Biological and Bioorganic Chemistry. Meet the Lecturer. Dr. Denis Svechkarev , PhD in Organic Chemistry Associate Professor, Department of Organic Chemistry, Faculty of Chemistry, Kharkov V. N. Karazin National University Senior Researcher, Department of Physical Organic Chemistry,

833 views • 37 slides

Nucleic Acids: Chemistry & Structure

Nucleic Acids: Chemistry & Structure. Andy Howard Introductory Biochemistry 8 October 2009. Nucleic acid chemistry Pyrimidines: C, U, T Purines: A, G Nucleosides & nucleotides Oligo- and polynucleotides. DNA duplexes and helicity DNA sequencing DNA secondary structure: A, B, Z

669 views • 57 slides

Biological and Bioorganic Chemistry

Biological and Bioorganic Chemistry. Some useful material. niichem.univer.kharkov.ua/physorg chemlaba.wordpress.com. What shall we do?.

472 views • 27 slides

Nucleic Acids and the Origin of Life

Nucleic Acids and the Origin of Life. 4 Nucleic Acids and the Origin of Life. 4.1 What Are the Chemical Structures and Functions of Nucleic Acids? 4.2 How and Where Did the Small Molecules of Life Originate? 4.3 How Did the Large Molecules of Life Originate?

605 views • 60 slides

Digestion of Nucleic Acids

Digestion of Nucleic Acids. By: Kristal, Dandre, and Zack. Nucleic Acids:. Genetic information that is passed on: DNA and RNA Found in all food sources that are from animals and plants. (DNA and RNA). Breakdown of nucleic acids: Mouth to Stomach. Mechanical Digestion: Mastication

642 views • 29 slides

Nucleic acids: the code of life

Nucleic acids: the code of life.

181 views • 15 slides

Chemistry of Nucleic Acids

Chemistry of Nucleic Acids. Nucleic acids (DNA and RNA) are made by joining nucleotides in a repetitive way into long polymers Nucleotides have three components (a) phosphate (b) sugar and (c) base Nucleoside is a sugar-base compound. Comparison of DNA and RNA.

114 views • 11 slides

THE NUCLEIC ACIDS

THE NUCLEIC ACIDS. Mrs Manisha Sane PGT Chemistry KV VSN NAGPUR. Two types of nucleic acid are found. Deoxyribonucleic acid (DNA) Ribonucleic acid (RNA). The distribution of nucleic acids in the eukaryotic cell. DNA is found in the nucleus

284 views • 28 slides

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Graduate student of Dr. Don Bergstrom investigates the Medicinal and Bioorganic Chemistry of Nucleic Acids.

Graduate student of Dr. Don Bergstrom investigates the Medicinal and Bioorganic Chemistry of Nucleic Acids.

Presentation Transcript

Principles of Bioorganic Medicinal Chemistry Drugs &amp; Medicinal Chemist

Isolation of Nucleic Acids

Metabolism of nucleic acids

Nucleic Acids: DNA, RNA and chemistry

Principles of Bioorganic Medicinal Chemistry Why Should Drugs Work?/ Biological Membranes

Structure of Nucleic Acids

Isolation of Nucleic Acids

3. Nucleic Acids – the acids of life

Nucleic Acids: RNA and chemistry

AMPLIFICATION OF NUCLEIC ACIDS

Hybridization of Nucleic Acids

Metabolism of nucleic acids

The biochemistry of nucleic acids

Biological and Bioorganic Chemistry

Nucleic Acids: Chemistry &amp; Structure

Biological and Bioorganic Chemistry

Nucleic Acids and the Origin of Life

Digestion of Nucleic Acids

Nucleic acids: the code of life

Chemistry of Nucleic Acids

THE NUCLEIC ACIDS

Principles of Bioorganic Medicinal Chemistry Drugs & Medicinal Chemist

Nucleic Acids: Chemistry & Structure