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Revolade 75mg tablets | Eltrombopag | MHP

Eltrombopag is sold under the brand name Revolade and it is a man-made form of a protein that increases production of platelets in your body @ MHP

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Revolade 75mg tablets | Eltrombopag | MHP

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  1. Revolade 75mg tablets | Eltrombopag | MHP DESCRIPTION Eltrombopag is sold under the brand name Revolade and it is a man-made form of a protein that increases production of platelets (blood-clotting cells) in your body. Revolade 75mg can reduces the risk of bleeding by increasing platelets in your blood. Revolade 75mgwhich is used asprescription drug under the guidance of the medical practioners

  2. INDICATION Revolade 75mg tablet isan anticancer medication which is; Indicated for the treatment of patients having Severe aplastic Anemia • First line treatment of severe aplastic Anemia • Treatment of refractory severe aplastic Anemia Indicated for the treatment to stimulate the growth and development of platelets in the bone marrow Primarily indicated for the treatment of patients having reduced platelet counts due to chronic hepatitis C virus infection MECHANISM OF ACTION Eltrombopag consist of class of drugs known as thrombopoietin (TPO) receptor agonists. A class of drugs is a group of medications which work in a same way. Eltrombopag mechanism by raising cells in your bone marrow and causes these cells to make more platelets. This effect reduces your risk of bleeding. PROPERTIES Ingredients : Eltrombopag Strength : 75mg Package : 7 tablets in a strip ADME Absorption: High plasma concentration is 2-6 hours Distribution: Maximum human plasma protein bounding is >99% and in blood plasma level is 50% to 79% Metabolism:

  3. generally metabolised via cleavage, oxidation and conjugation with glucuronic acid. Elimination: Revolade 75mg eliminated mainly via feces 59%, along with 31% via renally excreted Revolade 75mg Half-life for healthy patients is 21-23 hours and idiopathic thrombocytopenic purpura is 26-35 hours. DOSAGE MANAGEMENT • The usual dose for Chronic Hepatitis C-associated Thrombocytopenia is 25 mg PO qDay. Dose is managed in 25 mg accretion q2weeks PRN to attain target Plt needed to start/control antiviral therapy with pegylated interferon and ribavirin; not to exceed 100 mg/day • Severe Aplastic Anemia : 1.First-line therapy : When combination with standard immunosuppressive treatment, for patients with serious aplastic Anemia (SAA) The usual dose for severe Aplastic Anemia: 150 mg PO qDay for 6 months Avoid taking of more than starting dose; total duration is 6 months 2.Refractory SAA : In this condition the drug given who fail to respond enough to at least 1 before immunosuppressive therapy The usual dose for Refractory SAA: 50 mg PO qDay • The recommended dose for Chronic Immune Thrombocytopenia is 50 mg PO qDay Adjust dose to manage and control platelet count (Plt) >50 x 10^9/L to reduce the risk of bleeding; not to exceed 75 mg/day PRECAUTIONS • The drugRevolade 75mg tablet may have high risk of severe and probably life-threatening hepatotoxicity; monitor liver function before and during treatment • While receiving the drug, if patient with hepatic impairment (Child-Pugh Class A, B, C) initiates therapy for first- line treatment of severe aplastic Anemia, reduce initial dose • When treatment, If the patients have cataracts, do not use the drug due to the Revolade 75mg effects cataracts and make the condition worse. • Avoid theRevolade 75mg tablet while the patients have myelodysplastic syndrome (MDS), will increases the risk of death.

  4. • While on treatment with drug Revolade then Portal vein thrombosis reported in patients with chronic liver disease. SIDE EFFECTS Common side effects of Revolade 75mg : • Headache • Cough • Loss of appetite • Flu • Reduced red blood cells • Diarrhoea • Nausea • Fever • Weakness Serious side effects of Revolade 75mg : • Swelling of legs • Abdomen swelling • Confusion • Chest pain • Dyspnea • Cloudy vision • Urine in dark colour • Yellowing of your skin • Sensitivity to light • Seeing circles around lights PREGNANCY Pregnancy category is C Safety of drug during pregnancy is not established LACTATION During breast feeding, avoid using of drug Revolade 75mg STORAGE Store at room temperature 20°C and 25°C. CONTACT US PHONE NO: +91-9940472902 EMAIL: millionhealthpharmaceuticals@gmail.com WEBSITE:https://millionpharma.com/eltrombopag-75mg.php

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