has the consort statement improved the publication quality of early breast cancer randomised controlled trials in sy

Sep 09, 2011

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NCRI Conference - 3rd October 2007. CONSORT

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has the consort statement improved the publication quality of early breast cancer randomised controlled trials in sy

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1. Has the CONSORT statement improved the publication quality of early breast cancer randomised controlled trials in systemic treatment: a systematic review Clare Peckitt Clinical Trials & Statistics Unit (ICR-CTSU) Institute of Cancer Research, London, UK

2. NCRI Conference - 3rd October 2007

3. NCRI Conference - 3rd October 2007

4. NCRI Conference - 3rd October 2007

5. NCRI Conference - 3rd October 2007

6. NCRI Conference - 3rd October 2007

7. NCRI Conference - 3rd October 2007

8. NCRI Conference - 3rd October 2007

9. NCRI Conference - 3rd October 2007

10. NCRI Conference - 3rd October 2007

11. NCRI Conference - 3rd October 2007

12. NCRI Conference - 3rd October 2007

13. NCRI Conference - 3rd October 2007

14. NCRI Conference - 3rd October 2007

15. NCRI Conference - 3rd October 2007

16. NCRI Conference - 3rd October 2007

Defining Endpoints for Recurrence in Randomised Controlled Trials of Systemic Therapy for Early Breast Cancer: A Call fo

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Randomised Controlled Trials

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Trials of Adjuvant Trastuzumab in HER2+ Early-Stage Breast Cancer

Trials of Adjuvant Trastuzumab in HER2+ Early-Stage Breast Cancer. With permission from Hudis CA. N Engl J Med. 2007;357:39-51. ALTTO Formerly Known as APHRODITE. Inclusion Criteria • HER2+ breast cancer • ≥4 cycles anthracycline-based neoadjuvant chemotherapy • LVEF ≥50%.

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Lecture 5: Randomised Controlled Trials

Learning outcomes. Describe the key features of randomized controlled trialsCalculate measures of association used in randomized controlled trials. Randomised Controlled Trials . Ideal design for evaluating both the effectiveness and the side effects of new forms of interventionRCTs can be used t

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Rapid Critical Appraisal of Randomised Controlled Trials

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Randomised Controlled Trials in the Social Sciences Cluster randomised trials Martin Bland Professor of Health Statistic

Randomised Controlled Trials in the Social Sciences Cluster randomised trials Martin Bland Professor of Health Statistics University of York www-users.york.ac.uk/~mb55/. Cluster randomised trials Also called group randomised trials.

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Improving the reporting of randomised trials: CONSORT Statement and beyond

Improving the reporting of randomised trials: CONSORT Statement and beyond. Doug Altman The EQUATOR Network Centre for Statistics in Medicine, Oxford, UK. “The whole of medicine depends on the transparent reporting of clinical trials” Drummond Rennie, JAMA 2001.

794 views • 36 slides

Randomised Controlled Trials (RCTs)

Randomised Controlled Trials (RCTs). Graeme MacLennan. James Lind. Born Edinburgh 1716 On HMS Salisbury in 1747 he allocated 12 men with scurvy Cider Seawater Horseradish, mustard, garlic Nutmeg Elixir Vitriol Oranges and Limes . Think about… .

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Randomised controlled trials (RCTs). Methodologies for a new era summer school School of Applied Social Studies, University College Cork 22 June 2011 Dr Paul Montgomery Jennifer Burton. Aims. Questions RCTs might answer Main strengths and weaknesses How to conduct them

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Randomised Controlled Trials in the Social Sciences Conference 2009

Randomised Controlled Trials in the Social Sciences Conference 2009 Grouping in individually randomised trials Martin Bland Dept. of Health Sciences University of York, York, England http://martinbland.co.uk. Hidden samples The Wandsworth Terminal Care Study

707 views • 57 slides

Randomised Trials

Randomised Trials. Masoud Solaymani-Dodaran Iran University of Medical Sciences. How do we know a treatment works?. All who drink of this treatment recover in a short time, except those whom it does not help, who all die, it is obvious , therefore, that it fails only in incurable cases"

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Developing an Ontology for Randomised Controlled Trials

Developing an Ontology for Randomised Controlled Trials. Henry Potts & Sanjay Modgil Design-a-Trial team, University College London. Randomised controlled trials. ‘Gold standard’ in clinical research

226 views • 10 slides

Early Detection of breast cancer

Early Detection of breast cancer. Anthony B. Miller, MD, FRCP Associate Director, Research, Dalla Lana School of Public Health, University of Toronto, Canada. The problem. In low and middle income countries, breast cancer is usually diagnosed at an advanced stage

702 views • 31 slides

Treatment of Early Breast Cancer

Treatment of Early Breast Cancer. Frances Wright MD MEd FRCSC. Objectives. imaging & diagnosis historical overview of surgical treatment current practice breast surgery axillary staging. Radiologic Work-up. Common Mammogram Ultrasound Good for young women Usually targeted

880 views • 42 slides

The Safewards Randomised Controlled trial

The Safewards Randomised Controlled trial. Reducing Conflict and Containment on psychiatric wards. Lead by Professor Len Bowers. Conflict and containment. Containment. Conflict. Aggression Rule breaking Substance/alcohol use Absconding/missing Medication refusal Self-harm/suicide.

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Session 1 Randomised Controlled Trials

Session 1 Randomised Controlled Trials. Introduction – Study Design. We often wish to investigate the efficacy of new treatments and interventions on patient outcomes In this session, we shall consider a study design commonly used to answer such questions – Randomised Controlled Trials

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Sources of Bias in Randomised Controlled Trials

Sources of Bias in Randomised Controlled Trials. David Torgerson Director, York Trials Unit djt6@york.ac.uk www.rcts.org. Selection Bias - A reminder. Selection bias is one of the main threats to the internal validity of an experiment.

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Early Detection Of Breast Cancer

Early Detection Of Breast Cancer. A Formidable Challenge. CANCER. FEAR AND APPREHENSION. Introduction. Breast cancer is currently the most frequent cancer in women. There are more than one million cases occurring world wide annually.

1.71k views • 45 slides

Sources of Bias in Randomised Controlled Trials

Sources of Bias in Randomised Controlled Trials. REMEMBER. Randomised Trials are the BEST way of establishing effectiveness. All RCTs are NOT the same. Although the RCT is rightly regarded as the premier research method, by the cognoscenti, some trials are better than others.

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Second Annual Conference on Randomised Controlled Trials in The Social Sciences: The way forward

Second Annual Conference on Randomised Controlled Trials in The Social Sciences: The way forward The University of York, 13th - 14th September 2007 Hosted by ESRC Researcher Development Initiative and the York Trials Unit

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Anthropometry and Breast Cancer Publication

Anthropometry and Breast Cancer Publication. van den Brandt, P.A., et al. Pooled analysis of prospective cohort studies on height, weight and breast cancer risk. American Journal of Epidemiology. 2000; 152: 514-527. Cohort Studies in the Pooled Analysis of Anthropometry and Breast Cancer.

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Randomised Controlled Trials – Are They Always the Gold Standard?

Randomised Controlled Trials – Are They Always the Gold Standard?. A/Prof jane WarlaND. stillaware.org/usa2. Learning objectives. After attending this presentation attendees will: Discuss findings from recent RCTs (particularly AFFIRM)

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