Know about the Study of Biochemical Fixation Stability | Miraclus

1. KNOW ABOUT THE STUDY OF BIOCHEMICAL FIXATION STABILITY Surgeries of pedicle screws are not unknown to many nowadays as an accompaniment surgery with spine fusion surgery. The pedicle screw fixations after surgery support the healing area of the spine. There are certain conditions under which the pedicles can break. When screws are inserted through these pedicles, they can break. The pedicle's strength or the small space where the screws are being inserted can lead it to break. It is still not clear that when these pedicles break these screws are loosened, at the same time. The damage of surgical plates and screws may affect the healing. There is the pedicle screw fixation experiment that can show what happens to the screw if the pedicles break or they stay unharmed. The pedicle screw loosening: The process of pedicle screw fixation is often noticeable in the treatment of spinal disorders and infections. With time the procedure has evolved as a safe and secure way of treating a specific disorder, and only a percentage of 0.6% to 13% may show an incidence of screw loosening. As screw loosening is a significant concern for these surgeries, researchers can identify what causes the screw to loosen up and how it affects the healing process. Hard pedicles or insufficient diameter of the pedicle may be a reason for broken pedicles or loose screws. Here is a study that shows an experiment procedure of pedicle screw fixation with a series of tests to see how the conditions of pedicles or the length of the screw can cause the loosening of screws or broken pedicles. Experiment: There can be a biochemical study that can show the condition of the screws in the pedicles. The experiment used a set of Thirty L4 sawbones. It would work as the intact pedicles, semi pedicles, and non-pedicles for the researchers to insert screws in them. To check the result three different sizes of polyaxial screws of 6.0 mm × 45 mm, 6.0 mm × 50 mm, and 6.5 mm × 45 mm, were taken. During the experiment, the researcher will randomly insert the screws into the intact-pedicle group (IP group, n = 30), the semi-pedicle group (SP group, n = 15), and the non-pedicle group (NP group, n = 15), made with sawbones. The researcher can also do an even distribution of the screws to further check the result of the study. A total of five trials are conducted for screws to get to an accurate conclusion.

2. Procedure: The result of the study was obtained based on the tests conducted: imaging, pullout testing, and the embedded bone volume. No defects or fractures caused to vertebrae, while recording, screw insertions. Ensuring an appropriate result was essential. Hence, the researchers confirmed the particular screw trajectory and insertional depth with the help of the axial and sagittal X-ray imaging process. The process is carried out before removing the screws. Results/ Observations: For the experiment, the pullout strength of 41% to 45% for the SP group pedicles and 29% to 39% for the NP group pedicles was obtained after breaking the pedicles. However, for the NP group (p < 0.05), using screws with larger diameters can be less damaging and more effective. There was also a test of embedded bone volume conducted. Moreover, the procedure result went through the process of analysis to know how it works. The results show, when it is compared to the IP groups, the effective percentage for the SP group was 68% to 76%, whereas, for the NP group it was 58% to 65%. Inferences: There are certain inferences that the researchers can obtain from the whole experiment. ● There found no apparent correlation between the embedded bone volume of the pedicles and the pullout strength of the screws. It was also inferred that there is a relationship between the less effective bone volume and lower pullout strength. ● The study can show the objectives and results of the screw pullout tests on the broken pedicle Sawbones testing model. ● The pedicles and their conditions are crucial to find out the pullout strength of the screws. ● The study also shows that when a Medical practitioner works on a practical case of broken pedicles with a clinical approach, using longer screws with larger diameters can be more effective and less damaging.

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