1 / 6

BET Inhibitors, A Novel Advancement for the Treatment of Cancer and Other Diseases

The study analyzed that the BET inhibitors pipeline comprised 38 drug candidates in different stages of development. The high prevalence of cancer across the globe fuels the extensive research and development for BET inhibitors.

NidhiNehani
Télécharger la présentation

BET Inhibitors, A Novel Advancement for the Treatment of Cancer and Other Diseases

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. BET Inhibitors Pipeline to Witness Huge R&D Investment in the Coming Years

  2. BET Inhibitors Pipeline Analysis According to a new research report “Global Bromodomain and Extra-Terminal (BET) Inhibitors Pipeline Analysis, 2017 - Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments”, published by P&S Market Research, BET inhibitors currently exhibit a strong pipeline with estimated 38 drug candidates. Browse the Report Summary at: https://www.psmarketresearch.com/market-analysis/bet-inhibitors-pipeline-analysis BET inhibitors offer novel therapeutic approach for cancer The study analyzed that the BET inhibitors pipeline comprised 38 drug candidates in different stages of development.

  3. BET Inhibitors Pipeline Analysis Insights on pipeline segments As per the findings of the research, most of the BET inhibitor pipeline drug candidates are being developed to be administered by oral route. IC50 value and Kd of different types of BET inhibitors In BET inhibitors, IC50 value is measured as the concentration of drug at which 50% of the target is inhibited. IC50 is a pharmacokinetic measure; the lower the IC50 of drug candidate, the lesser the desired effect, and the less likelihood of the drug to have some off-target effect. Kd is known as dissociation constant of drug. It measures the rate of dissociation of the drug and its binding affinity. Birabresib (MK8628), a BET inhibitor by Merck & Co., has IC50 value of 100nM.

  4. BET Inhibitors Pipeline Analysis Strategic collaborations for the development of BET inhibitors The research finds that different companies are collaborating for the development of BET inhibitors. In January 2017, ConverGene had entered into a sponsored research agreement with the University of Maryland, Baltimore to investigate the in vivo anti-leukemic effects of ConverGene’s lead BET inhibitor drug candidates, CG223 and CG250. Some of the key players developing BET inhibitors are Resverlogix Corp., GlaxoSmithKline plc, Bristol-Myers Squibb Company, and others.

  5. BET Inhibitors Pipeline Analysis Download report sample at: https://www.psmarketresearch.com/market-analysis/bet-inhibitors-pipeline-analysis/report-sample

  6. GET IN TOUCH THANK YOU! For information regarding permissions and other queries Kindly write to: US/Canada Toll-Free: 1-888-778-7886

More Related