Toxicological Data System

1. Toxicological Data System CDR Gary Perlman, US Public Health Service Agency for Toxic Substances and Disease Registry 7May2008

2. Toxicological Data System: PDAs • Data System Overview • PDA Overview • Resources • Usage • Hardware/software • Contacts

3. Toxicological Data System: PDAs • Developed shortly after 911 for field use w/out need for laptop or internet • Ready reference of toxicological emergency values • Used in USA, CA, FR • Used by USCG, EPA, others…

4. PDA Overview • Icons are Programs • Programs Loadedby Tapping

5. PDA Overview Field Use • Assist - EPA (Chemical spills) • Inform - First Responders (share data) • Reply - to Citizen’s request at Meetings • Prepare - phone, fax, email list Share data via infrared beam

6. Resources • One database contains the following: • AEGLs (Exposure Guideline Levels) • ATSDR Toxicological Profiles (full text-172 chemicals) • ATSDR ToxFAQs (1 page summary-172 chemicals) • ATSDR Medical Management Guides for Acute Exposures to Chemicals MMGs (50 chemicals) • DOE PACs • EPA Risk Based Concentrations (RBC), Preliminary Remediation Goals (PRG) • EPA IRIS database (560 chemicals) • Occupation Levels • NIOSH RTECS: Registry of Toxic Effects of Chemical Substances

7. Resources (cont.) • These resources are saved as individual databases: • AFRRI Medical Mgmt of Radiological Causalities • ATSDR Risk Communication Primer • DOT Emergency Response Guidebook, and Spills (as a stand alone database) • National Library of Medicine’s HSDB (Hazardous Substances Data Bank for 5,000 compounds) • USAMRIID Handbook Medical Mgmt of Biological Casualties • USAMRICD Handbook Medical Mgmt of Chemical Casualties

8. Hardware 256 MB SD card SD card Reader/Writer PDA with SD slot

9. Software iSilo Document reader ($20) www.store.isilo.com

10. Anthrax Decontamination, ClO2 Dec2007 – Danbury, CT • Containment Breach Scenario • What is IDLH (5ppm) • What is Community Level (0.001ppm)

11. Databases Every database is an iSilo “document” The file you will use most is called: “Toxicological data for PDAs” Other iSilo document include: HSDB, ERG2004, and Medical Management of… Biol, Chem, Rad Casualties; Risk Communication Primer; and Environmental Glossaries (English and Spanish)

12. Usage Tap the iSilo icon

13. Usage Tap on the database name to open it.

14. Usage Tap on the database name to open it. This is the Emergency Response Guide These are the Bio, Chem, Rad, Casualties Guides This is the main database

16. Medical Management Guides

17. Medical Management Guides

18. Toxicological Profiles

19. Toxicological Profiles Hyper-Links from Table of Contents.

20. ToxFAQs

21. Risk Communication Primer

22. Hazardous Substances Data Bank (HSDB)

23. Hazardous Substances Data Bank (HSDB)

24. DOE’s Protective Action Criteria

25. Medical Management of Biological Casualties

26. Medical Management of Biological Casualties

27. Medical Management of Chemical Casualties

28. Medical Management of Chemical Casualties

29. Medical Management of Radiological Casualties

30. Medical Management of Radiological Casualties

31. RTECS

32. Usage Tap the iSilo icon

33. Usage Tap on the main database: Toxicological data for PDAs

34. Usage Tap on Introduction

35. Usage Tap on Go to Topto return to the start page.

36. Usage Tap onTable of Contents

37. Usage Tap on the first character of the chemical (e.g. B)

38. Usage Tap on the first three characters of the chemical (e.g. Ben)

39. Usage Scroll UporDownto locate the chemical. You can also tap and hold the stylus in the WHITE area to drag the page either up or down.

40. Usage Tap on the database (e.g. AEGL)

41. AEGL definitions Usage

42. AEGL data Usage

43. AEGL data (cont…) Usage

44. IRIS Usage

45. IRIS RfD summary Usage

46. IRIS RfD summary Usage

47. Medical Management Guides (MMG) Usage

48. Medical Management Guides (MMG) Usage

49. Minimal Risk Levels (MRL) Usage

50. Minimal Risk Levels (MRL) Usage