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Nivolumab is a generic form of brand name Opdyta 40mg which is a targeted therapy drug presently used to cure from melanoma, non-small cell lung cancer or kidney (renal cell) cancer , it belongs to a group of cancer drugs known as monoclonal antibodies, it is also known as an immune checkpoint inhibitor @ Apple Pharmaceuticals
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Nivolumab Opdyta 40mg injection
Description • Indication Nivolumab is a generic form of brand name Opdyta 40mg which is a targeted therapy drug presently used to cure from melanoma, non-small cell lung cancer or kidney (renal cell) cancer. Opdyta 40mg belongs to a group of cancer drugs known as monoclonal antibodies. Opdyta 40mgis also known as an immune checkpoint inhibitor. Sometimes these drugs are called targeted therapies because they target specific proteins (receptors) on the surface of cells. • Opdyta 40mg is indicated for the treatment of patients having conditions like : • • Melanoma which has spread or can’t be removed with surgery • • Non-Small Cell Lung Cancer which has spread or come back after chemotherapy • • Kidney (Renal Cell) Cancer which has come back after chemotherapy.
Opdyta recommended dosage for unrespectable or metastatic melanoma : • As single agent is either 240mg every 2 weeks or 480mg every 4 weeks given as IV infusion over 30 minutes until disease progression or unacceptable toxicity • With ipilimumab. The recommended dose of Opdyta is 1mg/kg administrated as an intravenous infusion over 30 minutes, followed by ipilimumab 3mg/kg given as IV over 90 minutes on the same day. Duration 3 weeks of max 4 doses, after completing combination dose continue the single agent treatment • For adjuvant treatment of melanoma : • As single agent is either 240mg every 2 weeks or 480mg every 4 weeks given as IV infusion over 30 minutes until disease progression or unacceptable toxicity for up to 1 year. • For Non-small cell lung cancer : • As single agent is either 240mg every 2 weeks or 480mg every 4 weeks given as IV infusion over 30 minutes until disease progression or unacceptable toxicity. • For small cell lung cancer : • As single agent is either 240mg every 2 weeks given as IV infusion over 30 minutes until disease progression or unacceptable toxicity for up to 1 year. Dosage and administration
Pregnancy and lactation • Storage • Store at under refrigeration at 2°C to 8°C. The effects of Opdyta 40mg are expected to be greater during the second and third trimesters of pregnancy. There are no available human data informing the drug-associated risk. Advise pregnant women of the potential risk to a foetus. Opdyta 40mg Excretion in human breast milk is not known; advise women to discontinue breastfeeding during treatment • Missed Dose • If you missed a dose take it as soon as possible, if time reach for next dose, then skip missed dose and continue regular schedule. Avoid taking two doses at a time. Avoid taking missed dose within 12hrs of the next dose.
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