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Insights into Diverse C-type Heme Proteins: Structure and Function

This exploration delves into various C-type heme proteins, such as PhnAb, BphA3, and PhtAc, examining their unique structures and roles in biological systems. The study highlights their electron transfer capabilities, binding motifs, and responses to environmental changes. Additionally, we explore the genetics and biochemistry underlying these proteins, shedding light on their evolutionary significance and potential biotechnological applications. Understanding these proteins provides insights into redox processes and can inform advancements in bioengineering and synthetic biology.

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Insights into Diverse C-type Heme Proteins: Structure and Function

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  1. [3Fe [3Fe - - 4S] 4S] Fdx3_RW1 Fdx3_RW1 - - C C CGYRL CGYRL C C VE VE --- --- RE RE C C - - PhdC_KP7 PhdC_KP7 - - C C QGYGN QGYGN C C IT IT --- --- RS RS C C - - PhtA3_DBF63 PhtA3_DBF63 Fd-I - - C C QGYAN QGYAN C C VV VV --- --- RS RS C C - - PhtAc_PYR PhtAc_PYR - - 1 1 ([3Fe ([3Fe - - 4S] 4S] - - type) type) - - C C QGYAN QGYAN C C VV VV --- --- RS RS C C - - PhtAc PhtAc _ 12B _ 12B - - C C QGYAN QGYAN C C VV VV --- --- RS RS C C - - PadAc2_RHA1 PadAc2_RHA1 - - C C T T H H GA GA ----- ----- E E C C PL PL H H - - PahAb_OUS82 PahAb_OUS82 - - C C T T H H GA GA ----- ----- E E C C PL PL H H - - NahAb_9816 NahAb_9816 - - 4 4 CarAc_CA10 CarAc_CA10 - - C C T T H H GI GI ----- ----- E E C C PF PF H H - - PhnAb_AFK2 PhnAb_AFK2 - - C C T T H H EV EV ----- ----- E E C C AM AM H H - - - - C C T T H H AV AV ----- ----- E E C C PL PL H H - - CarAc_CB3 CarAc_CB3 Fd-II - - C C S S H H AD AD ----- ----- E E C C TL TL H H - - BphA3_RHA1 BphA3_RHA1 ([2Fe ([2Fe - - 2S] 2S] - - type) type) - - C C T T H H GD GD ----- ----- E E C C TL TL H H - - TodB_F1 TodB_F1 - - C C T T H H GE GE ----- ----- E E C C SL SL H H - - BphA3_KKS102 BphA3_KKS102 - - C C T T H H GD GD ----- ----- E E C C SL SL H H - - BphF_LB400 BphF_LB400 - - C C T T H H GD GD ----- ----- E E C C SL SL H H - - BphA3_KF707 BphA3_KF707 [2Fe [2Fe - - 2S] 2S]

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