2007 Annual Meeting Northeastern Association of Graduate Schools

1. 2007 Annual MeetingNortheastern Association of Graduate Schools A Professional Science Master’s Degree in Molecular Biotechnology Ali Eskandarian Associate Dean, College of Professional Studies The George Washington University March 22, 2007

2. Outline • A Brief history of the CGS/Sloan grant at GW • Why Molecular Biotechnology? • Necessary partnerships • External and internal • Marketing and recruitment • More marketing • Addressing the difficulties

3. A Brief History • Sloan and Ford grants at CGS • Financial Mathematics, Proteomics, Dual diagnosis (substance abuse and mental illness), Museum & social service, Fine art and art appraisal • From Planning to Implementation • Molecular Biotechnology • Housing the degree inside the institution • College of Professional Studies

4. Partnerships • Internal partnerships • Champions among the faculty • A friendly central administration • Anticipating the obstacles • External partnerships • Essential for internships • Helpful in grounding the curriculum in marketplace realities • Helpful in marketing the program to both internal and external constituents

5. Marketing & Recruitment • Internal efforts • Never enough resources, use every tool available • direct mail, advertising, poster and brochure production, info sessions, web presence, press release, visits to other institutions • Establish a dialog between the key faculty and the marketing reps as early as possible • External efforts • CGS, Congress, Associations …and more

6. Difficulties • Administrative nightmares • Faculty ownership, course ownership, etc. • Student preparation • Background non-uniformity, and remedies? • Advising and mentoring • Advising early and often by faculty • Mentoring and help from students • Strategies for cohesion (topical seminars)

7. The End Any Questions? Would you like to review (quickly) what we present in our Info Sessions?

8. A New Master’s Degree inMolecular BiotechnologyUnique Preparation for a Biotech Career College of Professional Studies The George Washington University Thanks for joining us. The session will begin shortly.

9. Ali Eskandarian, Ph.D. Associate Dean College of Professional Studies ali.eskandarian@gwu.edu (202) 994-8192 Mark Reeves, Ph.D. Program Director and Professor Department of Physics Columbian College of Arts and Sciences reevesme@gwu.edu (202) 994-6279 Richard Donnelly, Ph.D. Program Co-director, Chair and Professor Department of Information Systems and Technology Management School of Business rgd@gwu.edu (202) 994-7155 Faculty Leadership Group

10. The George Washington University • Established in 1821 by Congressional Charter • 9 Schools, including the College of Professional Studies (CPS) • Over 20,000 students – including 10,000 graduate and professional students • Campuses at Foggy Bottom & Mt. Vernon (DC) and Loudoun County (Virginia) • Graduate Centers in Alexandria, Arlington, Ashburn, and Hampton Roads, Virginia • Contract programs for corporate and government clients offered on site

11. Biology is undergoing profound changes and the biotechnology industry is a strong disruptive force. The biotech/medical device industry is the fastest growing in the United States today. Universities and industry now collaborate very effectively in applied science areas. The impact is global and profound, and a new educational approach is needed to keep up. The Biotech Revolution! “The dominant science of the 21st century will be biology” – Freeman Dyson, physicist, futurist and Templeton prize winner

12. Winning concepts for new technologies and devices emerge from imaginative exploitation of discoveries in biological science and physics. Successful biotech products and processesare developed through effective integration of math, computer science and engineering. Greatly enhanced innovation in biotechnology is achieved through incorporation of appropriate business strategies and methods. Why Molecular Biotechnology?

13. A Science Bachelor’s degree is inadequate preparation for meaningful placement in Biotech. The common next step in science, the Ph.D., is a big step, intended as preparation for a research career. GW’s new Professional Master’s degree is the right preparation for entry into the biotechnology field, or later for a Ph.D. GW’s Master’s in Molecular Biotechnology (MMB) appropriately cuts across the disciplines of physics, biology and business, as a traditional Master’s cannot. Why a Master’s in Molecular Biotechnology?

14. Traditional Academic Disciplines Applied Science & Engineering Math Biology Chemistry Physics Computing Statistics

15. Physics of Biotech Devices Systems Biology Computer Science & Informatics New Interdisciplinary Biotech Business & Innovation

16. Build on basic principles in molecular biology, device physics, and modeling for the development of innovative new technologies and products. Integrate scientific and technical expertise with successful business practices in technology management and innovation. Develop effective team work and leadership skills in projects focused on new product development and technology venture concept creation. Apply classroom learning in structured internships with well-defined projects and goals in local industry, government and non-profit entities. Educational Objectives of GW’s MMB

17. Cell Division (Mitosis) DoublingDNA R CellGrowth Cyclin-Cdk binding in cell cycle Biology Cell Division (Mitosis) – depends upon Cdk2-cyclin binding

18. HIV Genome Cyclin-Cdk binding in cell cycle Biology Medicine Cdk-Cyclin binding is essential for HIV-1 Replication

19. Cyclin-Cdk binding in cell cycle Biology Physics Medicine Computational Prediction: Small peptide fits into binding Cdk binding site Cyclin-Cdk complex can’t form (Physics)

20. ~95% HIV activity suppression GW Medical School PBMC Infection (HIV - 1 UG/92/029, SI) 1200 1000 800 PBMC PBMC + SI p24 (pg/ml) 600 PBMC + SI + WT peptide PBMC + SI + 41/44 peptide 400 200 0 0 6 12 18 24 Days Post Infection Cyclin-Cdk binding in cell cycle Biology Physics Medicine Biochem F. Kashanchi, GWU, MC

21. Technological response (vaccine development) • Successful Innovation is not Assured • Discovery . . . Development . . . Deployment • Scientific discovery is only the first step • Additional R&D may lead to a prototype • Prototype trials may lead to market launch • Launch may lead to commercial success • As innovation proceeds, business decision-making and technology management play a greater and greater role, for good or bad. Biology Physics Medicine Biochem Business

22. Learn to Avoid and Repair . . . Case: Promising discoveries are repeatedly ignored by management, and an industry leader declines. Case: A slow, mistake-ridden development project kills what would have been a successful new product. Learn to Identify and Promote . . . Case: A team of scientists develops a strong venture concept and gives birth to a future industry giant. Case: Powerful innovation assessment tools are used to identify opportunities and successfully exploit them. Business Cases You’ll Learn to Address

23. Curriculum Highlights • Physics of Biotechnology focuses on the connection between understanding basic knowledge and applying that knowledge to the development of new devices. • Genomics, Proteomics, and Bioinformatics are at the forefront of the biotechnology revolution, providing new insights about the biodiversity of life on our planet, and impacting biomedical research by leading the way to new therapies for genetic and microbial diseases.

24. Curriculum Highlights • Management of Innovation equips students with methods useful in identifying opportunities and developing new technical products, including new management approaches and key ethical issues. • Technology Entrepreneurship/Intrapreneurship emphasizes the creation of new biotechnology ventures and developing new business proposals within firms. Technology Commercialization focuses on competitive analysis, shortening time-to-market, and marketing biotechnology products.

25. Curriculum Highlights THE CAPSTONE PROJECT Students integrate the knowledge and skills learned in the Molecular Biotechnology program in a six- to twelve-month project tackling real industry problems through either independent guided research and writing or team projects.

26. Sample Course Schedule

27. Sample Course Schedule

28. Careers in Molecular Biotechnology You will develop the working knowledge to move flexibly between the lab bench and biotechnology management. At the lab bench: new devices electronics sensors vaccines drug delivery biochemistry genetic engineering In management: new product concepts project management product marketing product line management entrepreneurship venture capital consulting

29. Admissions • Bachelor’s degree in a relevant field of science, applied science or engineering • Minimum GPA of 3.0 • GRE results • Statement of purpose • At least two letters of recommendation • Admissions decisions on rolling basis For additional information, please visit www.gwu.edu/gradinfo

30. Program Contacts Mark Reeves Program Director reevesme@gwu.edu Richard Donnelly Program Co-director rgd@gwu.edu Lynn Griffin Program Representative griffinl@gwu.edu College of Professional Studies The George Washington University 805 21st Street NW, Suite 301Washington, DC 20052 202-994-2083 Fax: 202-994-7718

31. Additional Contacts • GWU Information (202) 994-4949 • Admissions Office (202) 994-6210 • Financial Aid Office (202) 994-6620 • Registrar’s Office (202) 994-4900 • Veteran’s Benefits (202) 994-4925 • On the web http://www.cps.gwu.edu

32. Careers in Molecular Biotechnology You will develop the working knowledge to move flexibly between the lab bench and biotechnology management. At the lab bench: new devices electronics sensors vaccines drug delivery biochemistry genetic engineering In management: new product concepts project management product marketing product line management entrepreneurship venture capital consulting