UTERINE ARTERY VELOCIMETRY AT MIDGESTATION AND ADVERSE PREGNANCY OUTCOME IN LOW RISK PRIMIGRAVIDAE

1. UTERINE ARTERY VELOCIMETRY AT MIDGESTATION AND ADVERSE PREGNANCY OUTCOME IN LOW RISK PRIMIGRAVIDAE Angela Emanuel, Prof. Syeda Batool MazharMaternal and Child Health Center, Pakistan Institute of Medical Sciences, Islamabad, Pakistan OPTIONALLOGO HERE OPTIONALLOGO HERE Objectives Screening Characteristics 2nd trimester Resistance Index for adverse pregnancy outcome Outcome measures Pregnancy Outcome in study cohort (n=172) To determine the relationship between abnormal uterine artery velocimetry at midgestation and adverse pregnancy outcome in low risk primigravidae Methods Statistics Chi- Square test was used to find out the significance of Abnormal uterine artery Doppler in prediction of adverse pregnancy outcome Discussion • Discussion • Previous studies have reported a sensitivity of 33.3% and a specificity of 92.8% in prediction of adverse outcome in low risk pregnancies • Whether RI or PI is a superior parameter in prediction of adverse outcome- controversial • Due to low sensitivity Uterine artery Doppler is not an effective screening tool Abnormal uterine doppler & adverse pregnancy outcome Results Characteristics of the study cohort (n= 172) Conclusions • Abnormal uterine artery Doppler is associated with adverse peri-natal outcome. • Does not qualify as a screening tool in low risk population due to low sensitivity. • If resources available this test should be done at 20 to 24 weeks during the anatomical survey as it is not time consuming and is cost-effective . Uterine artery Doppler in study cohort References • Costa SL, Proctor L, Dodd JM, Toal M, Okun N, Johnson JA, etal.Screening for placental insufficiency in high-risk pregnancies: is earlier better? Placenta. 2008; 29:1034-40. • Park YW, Lim JC, Kim YH, Kwon HS. Uterine artery Doppler velocimetry during mid-second trimester to predict complications of pregnancy based on unilateral or bilateral abnormalities. Yonsei Med J. 2005 31; 46):652-7. • Vainio M, Kujansuu E, Koivisto AM, Mäenpää J. Bilateral notching of uterine arteries at 12--14 weeks of gestation for prediction of hypertensive disorders of pregnancy. Acta Obstet Gynecol Scand. 2005; 84:1062-7. • Simanaviciūte D. [Significance of early diastolic notch in the prognosis of unfavorable pregnancy outcome] Medicina (Kaunas). 2003;39:659-68. Screening Characteristics 2nd trimester Pulsatilty Index for adverse pregnancy outcome