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caALK1

B. MEEC. - TGF- b. - TGF- b. Oligofect. +TGF- b. +TGF- b. siRNA-PP1 a. siRNA-Ctrl. -. -. PP1 a. actin. MEEC BRE-luc. 14. 12. 10. Luciferase activity (arbitrary units). 8. 6. 4. 2. 0. -. +. -. +. -. -. +. +. PP1 a :. MEEC. A. caALK1. caALK5. Smad7. Marker.

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caALK1

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  1. B. MEEC -TGF-b -TGF-b Oligofect. +TGF-b +TGF-b siRNA-PP1a siRNA-Ctrl. - - PP1a actin MEEC BRE-luc 14 12 10 Luciferase activity (arbitrary units) 8 6 4 2 0 - + - + - - + + PP1a: MEEC A. caALK1 caALK5 Smad7 Marker 30 min LacZ H2O 1h 2h 4h - PP1a PP1b PP1g Id1 actin C. MEEC (CAGA)12-luc 160 140 120 100 Luciferase activity (arbitrary units) 80 60 40 20 0 - + - siRNA-PP1a: siRNA-PP1a: - - + PP1a:

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