List of medications of Multiple myeloma

1. List of medications which are helpful in the treatment of Multiple myeloma

2. About Multiple Myeloma: Multiple myeloma is a type of blood cancer that forms in plasma cells found in the bone marrow. Plasma cells are a type of white blood cell that produces antibodies in the bone marrow to help your body fight infections and diseases. Or Multiple myeloma is also known as simple myeloma or Kahler's disease. It is a cancer of the Plasma cell which is a type of white blood cell that produces antibodies and helps in fighting against infections and germs.Multiple myeloma leads to accumulating cancerous cells in bone marrow or lymph with. With this effect, the plasma cell produces an abnormal protein that in result produces abnormal antibodies that lead to complications.

3. Symptoms of Multiple Myeloma In the case of multiple myeloma, there are no initial symptoms however the symptoms appear as the disease progresses. The signs and symptoms are: • Constipation  • Frequent infection  • Bone pain  • Constipation  • Nausea  • Confusion  • Excessive thirst  • Weight loss  • Weakness  • Numbness in hand and feet

4. Multiple Myeloma medications There are a few medications that are helpful in the treatment of multiple myeloma. These drugs either work by strengthening the immune system of the body by increasing the number of plasma cells or by blocking the survival activity of cancerous cells.  • Lenalidomide • Pomalidomide • Carfilzomib • Bortezomib • Ixazomib • Panobinostat • etc

5. Lenalidomide: Lenalidomide is a thalidomide analog drug that is used in the treatment of multiple Myeloma when combined with dexamethasone, inpatient who has received at least one previous therapy. It is also used in the treatment of mantle cell lymphoma and in myelodysplastic syndrome(MDS). • Pomalidomide: Pomalidomide is a thalidomide analog that is used in the treatment of multiple myeloma, in combination with dexamethasone. This medication is used on the patient who has at least two previous therapies of lenalidomide and proteasome inhibitor class drug. • Carfilzomib: Carfilzomib is a proteasome inhibitor class drug which should be administered within 60 days of completion of the last therapy.This medication comes in a single wild which contains 60mg of carfilzomib. This is injected intravenously at alternative days for at least two to three weeks.

6. Bortezomib This drug was the first drug to be approved for the use of multiple myeloma. This drug has a major advantage to be used in a patient having multiple myeloma and suffering from kidney problems. This is available in injection form and is injected intravenously once or twice a week. • Ixazomib This drug belongs to a proteasome inhibitor class drug that is used for the treatment of Multiple Myeloma. This is available in capsule form and should be taken orally once a week followed by three weeks. • Panobinostat This drug belongs to histone deacetylase inhibitors class drug that is used in the treatment of multiple myeloma who have already been treated with bortezomib and immunomodulating agent. This is available in capsule form and should be taken 3 times a week.

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