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This study by Viros et al. in Nature delves into the genetic underpinnings of melanomas caused by ultraviolet radiation, shedding light on the mechanisms that drive skin cancer. By analyzing the genome of UVR-induced melanomas, the researchers identified key mutations and pathways involved in tumor development. The findings provide valuable insights for potential therapeutic strategies and personalized treatments for melanoma patients. This research advances our understanding of the complex interplay between UV exposure and skin cancer, offering new perspectives on prevention and treatment approaches.
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Genome analysis of UVR-driven melanomas. A Viros et al. Nature 000, 1-5 (2014) doi:10.1038/nature13298