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Impact of Mannan on Symptom Severity in Mice Inoculated with Virus: A Study Analysis

This study investigates the effects of mannan co-administration on symptom severity and weight loss in mice inoculated solely with a virus. A total of 27 mice were divided into groups based on weight change and survival, with daily evaluations of symptoms recorded on a scale from no weight loss to death within two weeks. The results indicate the potential role of mannan in modifying viral infection outcomes. Detailed analysis will aid in understanding its therapeutic implications in viral diseases.

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Impact of Mannan on Symptom Severity in Mice Inoculated with Virus: A Study Analysis

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  1. Okayama/5/2000 Chiba/1001/2009 A 2×105PUF 10 5 Inoculated with virus solely Inoculated with virus + mannan n=9×2 0 2×104PUF 2×104PUF 10 Surviving mice 5 n=9×2 n=9×2 0 2×103PUF 2×103PUF 10 5 n=9×2 n=9×2 0 5 10 15 5 10 15 0 0 Day after infection B Symptom score 0: No weight loss 1: Max. weight loss ≦10% 2: Max. weight loss 10 < ~ ≦ 20% 3: Max. weight loss > 20% 4: Died within 2 weeks 20 n=27×2 15 Sum of mice n=18×2 10 5 0 0 1 2 3 4 0 1 2 3 4 Symptom score Inoculated with virus solely Inoculated with virus + mannan

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