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Genetic Variants in SLC2A9, ABCG2, and SLC22A12 Linked to Uric Acid Levels and Gout

This study by Reginato et al. (2012) explores the genetic factors contributing to hyperuricaemia and gout, specifically examining variants in the SLC2A9, ABCG2, and SLC22A12 genes. The research identifies associations between these variants and serum uric acid levels, shedding light on the underlying mechanisms of gout. Understanding these genetic influences enhances our knowledge of gout pathogenesis and may lead to improved therapeutic strategies for managing hyperuricaemia and gout-related conditions.

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Genetic Variants in SLC2A9, ABCG2, and SLC22A12 Linked to Uric Acid Levels and Gout

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  1. Table 2SLC2A9, ABCG2 and SLC22A12 variants associated with serum uric acid levels, FeUA and gout Reginato, A. M. et al.(2012)The genetics of hyperuricaemia and gout Nat. Rev. Rheumatol.doi:10.10.38/nrrheum.2012.144

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