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Supplemental Figure 2 illustrates representative sodium current recordings from a left atrial cardiomyocyte of a ΔKPQ mouse. The recordings depict responses to a depolarizing pulse from -100 mV to various test potentials ranging from -70 to 20 mV in 5 mV increments. Measurements were conducted in a sodium concentration of 130 mM at a bath temperature of 22°C. All recorded currents have been unfiltered and corrected for TTX effects, providing insight into the electrophysiological properties of these cardiomyocytes.
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Supplemental Figure 2 20 mV -70 mV -100 mV Supplemental Figure 2: Representive sodium current recordings from a left atrial cardiomyocyte from a ΔKPQ-mouse in response to a depolarizing pulse from -100 to test potentials ranging from -70 to 20 mV in 5 mV steps. Measurements were performed in 130 mM [Na]o at 22° C bath temperature. All currents are unfiltered and TTX-corrected.
