1 / 18

TRICHINELOZA

TRICHINELOZA. Defini ţ ie : - boal ă infec ţ ioas ă acut ă, - determinat ă de nematodul Trichinella spiralis - manifestat ă prin : - febr ă, - mialgii , - fenomene alergice. ETIOLOGIE. Vierme nematod, de 1,5-4 cm Genul Trichinella, familia Trichinelliadae.

beck-stevens
Télécharger la présentation

TRICHINELOZA

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. TRICHINELOZA • Definiţie: - boalăinfecţioasăacută, - determinată de nematodulTrichinellaspiralis - manifestatăprin: - febră, - mialgii, - fenomenealergice.

  2. ETIOLOGIE • Vierme nematod, de 1,5-4 cm • Genul Trichinella, familia Trichinelliadae

  3. EPIDEMIOLOGIE • Ciclul biologic integral în aceeaşigazdă: - larveînchistate in carneainfestata->intestin - eliberarealarvelor -> adulti in 5-7 zile - fertilizare -> masculieliminati in scaun -> femelelevivipare intra in mucoasa -> depunlarve (1500/1 femela) -> vase limfatice -> canal toracic -> sange -> tesuturi

  4. Tropisme: muschii striati - > chiste (50 zile-3 luni) • Gazde: - porc mistret - urs, vulpe - caine, pisica - sobolani - cal

  5. PATOGENIE Larvele viabile ingerate - > stomac - > intestin - > se matureaza in adulti masculi, femele - > microlarve - > circulatia generala - > canal toracic - > muschi striati scheletici -> larvele se inchisteaza Larvele pot migra si in miocard, SNC, pulmon, unde nu se inchisteaza.

  6. PATOGENIE

  7. PATOGENIE • Miozita (si miocardita) • Capilarita alergica • Infiltrat Loffler • Fenomene-neuropsihice

  8. CLINICA TRICHINELOZEI • Dependenta de doza de larve ingerata • Incubatia: 2-28 de zile (in medie 9-14 zile) • Stadiul intestinal: - dureri abdominale - diaree - anorexie, greata

  9. CLINICA TRICHINELOZEI • Stadiu de invazie musculara: perioada de stare - 20 - 30 zile - mialgii, tumefactia maselor musculare (tumefiere dureroasa), algii oculare - dificultate la masticatie, respiratie, mers - hemoragii subconjunctivale, chemozis

  10. - Eruptii urticariene - Edeme periorbitare, ale fetei

  11. CLINICA TRICHINELOZEI - febra 38-40 grade C - tulburari neuro-psihice: - cefalee, ameteli - confuzie - meningism -> coma - tulburari respiratorii: - tuse - expectoratie hemoptoica

  12. CLINICA TRICHINELOZEI - miocardita: - tahicardie - tulburari de ritm (galop) - modificari EKG Convalescenta: - coincide cu inchistarea larvelor in muschi - retrocedarea treptata a semnelor clinice

  13. Forme clinice • Usoare • Medii • Severe: - cu toxemie - fenomene neuro-psihice

  14. COMPLICATII • Nervoase: encefalita, meningoencefalita • Cardiace: miocardita • Vasculare (flebite, arterite) Decesul: prin soc infectios, miocardita, insuficienta respiratorie, casectizare progresiva

  15. DIAGNOSTIC POZITIV • Laborator: leucocitoza cu eozinofilie -> 10-70% (din saptamana II-III -> 6 luni) • Reactii intradermice • Reactii serologice: - precipitare larvara - teste de floculare: - cu bentonita - rapida, pe lama - test de microfloculare pe lama - RFC, aglutinare pe lama cu trichina-latex - ELISA • Biopsie musculara: saptamana 3-4 • Teste enzimatice: CPK, LDH, TGO

  16. DIAGNOSTIC DIFERENTIAL • Afectiuni mialgice: gripa, infectia cu Coxsackie, leptospiroza • Stari febrile: septicemii • Afectiuni neurologice: polinevrita, meningoencefalita • Dermatomiozita, polimiozita • Boli cu eozinofilie si febra: boala Hodgkin, leucemia cu eozinofile, periarteita nodoasa

  17. TRATAMENT • Igieno-dietetic: • repaus, • dieta cu calorii multe • Stadiul intestinal: • purgative • Vermifuge, albendazol • Antihelmintic: tiabendazol (mintezol) • Corticoterapie • Antihistaminice • Tratament patogenetic

  18. PROFILAXIA • Controlul trichinoscopic al carnii date la consum • Aplicarea si respectarea masurilor sanitar veterinare de prevenire a infestarii animalelor • Distrugerea larvelor din carnea infestata prin pastrarea bucatilor de carne de cca 15 cm grosime la -25 o C, 20 de zile • Prelucrarea termica corecta la > 75 o C • Raportarea cazurilor la organele sanitare - > ancheta epidemiologica

More Related