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Longer Life, Better Life

Longer Life, Better Life. ——Current research progress on Alzheimer Disease. The third group 陈昊. 21 st century--time for the aged. Number of the aged is so huge!. 0.7 billion is the old! Almost 1 in 10 on the world is over 60!. VS. October 31st, 2011 7 billion people on the world?.

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Longer Life, Better Life

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  1. Longer Life, Better Life ——Current research progress on Alzheimer Disease The third group 陈昊

  2. 21st century--time for the aged Number of the aged is so huge! 0.7 billion is the old! Almost 1 in 10 on the world is over 60! VS October 31st, 2011 7 billion people on the world?

  3. Aging is everywhere 4-5 times increasing in 50 years, just like a rocket! What about China? The pace is faster. Number of the aged (current and predicted) of some continent

  4. The Result: Enjoy a longer life CIA World Fact book 2007 : Over 100 nations or regions enjoy the life expectancy over 70! ? Quality of life? Life expectancy worldwide on 2007 From Wikipedia

  5. Living quality---A better life as well? The tragedy of aging: Economic influence Aging is good or not? This is a question. Social problems Health and diseases

  6. Diseases of the aged The position of Alzheimer When we become old…… Stroke CHF diabetes Aged diseases Cancer Neurodegenerative disease hypertension Alzheimer

  7. 1 The characters of Alzheimer 2 Alzheimer----the killer of life quality 3 Research on Mechanism of Alzheimer 4 Current drug and therapy 5 Can Alzheimer be prevented? Contents Fight against Alzheimer!

  8. 1 Alzheimer--- four stages characters Severe Early Middle Final • slow, progressive loss of intellectual ability • difficulty learning • mild depression • cannot speak or walk, even breathe • has profound memory loss • an increase in memory loss • Decrease losing of daily living ability • unable to recognize objects and family members Buckley LL; Schub T; Pravikoff D; Quick lessons about Alzheimer Disease. Cinahl Information Systems, 2011 Sep 30

  9. Epidemiology from a point: a large market in AD therapy • Drugs for AD have a large market. • AD is very popular in the aged.

  10. 2. Alzheimer destroys the quality of life Danger of the patients • They can’t remember what they have done. • They can’t remember their family members. • Finally, they will not know who they are. • They will die because of breath problem!

  11. Alzheimer destroys the quality of life Social problems Have you remembered or not? ! Mercy killing! TEMPORARY INSANITY: THE STRANGE LIFE AND TIMES OF THE PERFECT DEFENSE. Boston University Law Review. October, 2011. 1660-1661

  12. The mechanism Of Alzheimer Cholinergic hypothesis Amyloid hypothesis 3.The mechanism of Alzheimer—so many hypothesis amyloid deposits imbalance Acetylcholine (ACh) production elimination 11C-PIB PET images characteristic Christiane Reitz. Epidemiology of Alzheimer disease. Nat. Rev. Neurol. 7, 137–152 (2011)

  13. New research: The interaction between these hypothesis Amyloid hypothesis to Cholinergic hypothesis MagdolnaPa´ka´ski, Ja´nosKa´lma´n. Interactions between the amyloid and cholinergic mechanisms in Alzheimer’s disease. Neurochemistry International. 2008. 53. 103-111

  14. New research: The interaction between these hypothesis Cholinergic hypothesis to Amyloid hypothesis MagdolnaPa´ka´ski, Ja´nosKa´lma´n. Interactions between the amyloid and cholinergic mechanisms in Alzheimer’s disease. Neurochemistry International. 2008. 53. 103-111

  15. Current Drug H3 antagonist ACEIs 5-HT receptor New ACEIs 4.Current Drug and therapy Alvin V. Terry Jr, Patrick M. Callahan, Brandon Hall, Scott J. Webster. Alzheimer's disease and age-related memory decline (preclinical). Pharmacology, Biochemistry and Behavior 99 (2011) 190–210

  16. 5. Can Alzheimer be prevented? Antibody Therapy? Diet Therapy? Prevention Of AD Emotional Therapy? Anti- oxidation? Virus-like Vaccine?

  17. Mechanism clearer More drugs Better prevention Our love To the old? ---Longer life, better life Conclusion live longer, live better. It’s not only for the old, but also for our future!

  18. Thank You ! F0917101TM Scientific

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