Clinical Scenario

1. Clinical Scenario

2. Step 1: Ask an answerable clinical question--P. I. C. O. Patient / Problem : Intervention / Exposure: Comparison: Outcome:

3. PICO Question: • Patient / Problem : • Intervention / Exposure: • Comparison: • Outcome:

4. Step 2: Effective searches for the best Evidence

5. 搜尋策略的設計表 SEARCH STRATEGY DESIGN TABLE

6. 實際搜尋 ACTUAL SEARCHES

7. Step 3: Critically appraise that evidence for its validity and importance

8. A. Are the results of this clinical decision analysis valid?

9. 本文獻： □Yes □No □Unclear 評論Comment： 1. Were all the important therapeutic alternatives (including no treatment) and outcomes included?

10. 本文獻： □Yes □No □Unclear 評論Comment： 2. Are the probabilities of the outcomes valid and credible?

11. 本文獻： □Yes □No □Unclear 評論Comment： 3. Are the utilities of the outcomes valid and credible?

12. 本文獻： □Yes □No □Unclear 評論Comment： 4. Was the robustness of the conclusion tested?

13. B. Are the valid results from this decision analysis important ?

14. 5. Did one course of action lead to clinically important gains? 本文獻： □Yes □No □Unclear 評論Comment：

15. 6. Was the same course of action preferred despite clinically sensible changes in probabilities and utilities?

16. C.Are the valid, important results of this decision analysis applicable to our patient?

17. 7.Do the probabilities apply to our patient?

18. 8.Can our patient state his/ her utilities in a stable, usable form?