1 / 1

Characterization of E. coli O157:H7 LEE Cluster and Homologous Genes in Pathogenicity

This study investigates the pathogenic mechanisms of E. coli O157:H7, focusing on the LEE (Locus of Enterocyte Effacement) cluster genes such as cesD2, escUTSR, and espB. We explore the homologous relationships between key proteins, including SepL to YopN/TyeA and SepQ to YscQ/FliN, and their implications in bacterial virulence. The comparative analysis extends to Yersinia enterocolitica's Yop-Ysc cluster, shedding light on the evolutionary conservation of virulence factors across enteropathogenic bacteria.

bessie
Télécharger la présentation

Characterization of E. coli O157:H7 LEE Cluster and Homologous Genes in Pathogenicity

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. E. coli O157:H7 LEE cluster cesD2 escUTSR sepZ espB espA orf5 sepQ escF espD sepL eae tir escN escV rorf8 escC glrAR ler escD rorf3 escJ SepL is homologous to YopN/TyeA SepQ is homologous to YscQ/FliN rORF8 is homologous to YscI Orf5 is homologous to YscL/FliH Orf2 is homologous to YscE CesD2 is homologous to LcrR 1Kb yopM yopD yopB lcrV lcrR lcrD TyeA/YopN yscN yscP yscQ yscRSTU virF yscC yscD yscEFGHIJKL Y. enterocolitica Yop-Ysc cluster

More Related