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This study investigates the distribution and functionality of glutathione S-transferase (GST) genes in Anopheles gambiae and Drosophila melanogaster. By examining various GST isoforms, including GSTd1, GSTd2, and others, we aim to understand their roles in detoxification processes and insecticide resistance. The analysis incorporates genomic data, gene expression profiles, and phylogenetic relationships, providing insights into evolutionary adaptations and potential implications for vector control strategies.
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B A Anopheles gambiae agcp2052 GSTd9 GSTd7 agcp2459 GSTd1 GSTd2 GSTd8 GSTd5 2R 18B * DmGSTD5 * DmGSTD2 DmGSTD4 DmGSTD3 * DmGSTD7 GSTd6 GSTd4 * GSTd11 GSTd12 GSTd3 GSTd10 DmGSTD6 DmGSTD10 2R 19D DmGSTD1 1kb * DmGSTD8 DmGSTD9 GSTd2 GSTd1-5 GSTd1-3 * Drosophila melanogaster GSTd1-6 * GSTd1-4 GSTd9 GSTd3 GSTd6 GSTd8 GSTd10 GSTd1 GSTd2 GSTd4 GSTd5 GSTd7 CG17639 GSTd11 GSTd8 3R 87B GSTd6 * GSTd9 GSTd12 * GSTd3 * GSTd4 * GSTd10 * GSTd5 DmCG17639 * GSTd7 * GSTu2 * GSTu3 GSTu1 DmGSTS1