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Trends and Practices in Clinical Pharmacology: A Comprehensive Review

This article explores recent advancements and best practices in clinical pharmacology, emphasizing the role of effective communication among healthcare professionals and the importance of developing robust clinical guidelines. It highlights the need for ongoing education to keep pace with evolving pharmacological therapies and standards. A thorough analysis of case studies and regulatory policies illustrates the continuous improvement in patient care through safe and effective medication use. Key factors influencing clinical decisions and the integration of research into practice are also discussed.

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Trends and Practices in Clinical Pharmacology: A Comprehensive Review

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    1. ???????????? ??????? ???????????????? ? ???????????? ??????????????  ?.?. ??????????? ???. ???????? ??????????? ???????????? ????, ?????????  ??????? ??????????? ?????????? ?????????? ???????????? ?????? ???? EACPT ? AGAH

    2. ??????? ????????? ???????????? ????? ???????? ???????? • ????? ????????? ????? ? ?????? ???????? ???????? ???????????? ????????, ???? ?????? ?????: ??? ??????, ??? ??????, ????? ??????, ? ??????? – ????? •

    3. ????????? ? ???? ?? ?????? ???????????, ??????? ????? ?????? ???????? ???????? ?????????? ? ??????????? ??? ??????????, ? ? ????? ? ???? ?????? ???? ???????? ??????? ???????? ? ?????? ?????? ? ? ??????????? ?????????? •  

    4. ??????????? ???????????????? ????? ??????? ?????????? ????????????? ??????????  • ???????????? ???? ?????, ??????? ????? ?????????, ??????, ? ?????? ???????, ???????? ?? ????????? ????????   • ?????? ????? ?????????? ????????, ??? ?????????? ????????????? (????????????) ????????? ?? ??????????????? (????????????) ????????????? ???????

    5. ???????????? ????????????? ???????? — ??? ????????, ??????? ???????? ?????????????? ?????????????? ????????-???????????? ??? ????????-????????? ?????? ???????? ?? ??? ???????  • ?? ????????? ????? ???????? ??????? ??????? ?????? ???????????????? ???????? ?? ?????? ????????????? ??? ???????????? ????? ?????????????????? ???????? ???????? ? ????? ???????????? ??? ?????????????? ?????

    6. ??????? ????????????? ????????? ?????????? ? ??????? ?????????? ????????, ???????????? ? ????????????? ????????????? (???????????, ??????????????, ????????????, ?????????????? ???????????????????? ???????) ? ??????????? ???????????? ??????????? ?? ????????????? ? ???????????? ?? ?????? ? ??????? ?????????, ??????? ?????????? ? ????????? ? ??????? ??? ? ????????? ?????????? ?? ???? ??????? ????? ??????????? ?????????

    7. ??? ???????? ????????????? ????????? ????????? ??????????? ?????? Good Clinical Practice (????????? ??????????? ????????), ??? ??????? ???????? ?????????? ?????? • ???????????? ???????? ???????? ????????, ???? ???????? ???????? ? ?????? ?????? 10 ??? • ?? ???? ?????? ??????? ????????????? ????????? ?????? ??????? ??????? ?? ??? ???????? ? ???????? ??????? ??? ??????? ?????????? ???????? ? ??????? ??????????? ????????????

    8. ????????? ????????????? ?????????   • ??? ?????????????? ??????????? ?? ????? ?? ????????? ????? ???????? ???????   • ????????? ????? ???????? ????????? ????   • ????????? ????????? •

    9. ??????? — ??? ????????????? ????????, ??????? ?????????? ????? ????????? ????? ???????? ????????? ?????? ????????????? ?????????, ? ?? (?????? ???????? ????????), ????? ???????, ??? ?? ???????? ?????????????? ?????????????? ???????????????? ????????, ??????? ??? ??????????? ??? ??????? ?????? ????????? ?? ??? ?????????? ?? ???? ????????? ??????? ????? ????????????? ?????? ???????????????? ?????????, ?? ??? ??? ???? ???????????? ?????????

    10. ??????? ??????? ?? ????????????? ?????????, ??????? ???????????? ?? ?????? ????? ?? ?????? ??? ????????????? ????????? ??????? ?????????? ???????, ? ?????? — ???????? ???????????? ????????????? ??????? (Policy Relating to Generic Medicines in the OECD. Final report for the European Commission. NERA, S.J. Berwin & Co, YRCR Ltd., December, 1998) ???????? ????????? ???????????? ?????????, ???? ???????? ????????? ???? ??????? ?????, ? ?? ????? ??? ????? – ??? ?????????, ????????? ?????? ??????? ? ?????? ?????? ?????????? ?? ??????????

    11. ???????? ???????? ??????? ????? ??????? ???????, ??? ???????? ????????????? ????????? • ? ?????? ??? ??????????? ???????? ?????????? ?????????????? ??????????? ??????????, ???????? ? ???????????????? ????????? ????????? (????????????? ????????, ????????? ?? ???????????? ? ?.?.), ? ????? ?????? ? ?????????????????? • ????????? ???? ???????????? ?? ????? ??????

    12. ??? ???????, ??????? ????????? ?????????? 24 ???????? ???????????? ? ???????????? ???????????? ????????? ???????? ? ????? • ?????? ?????????? ?????????????????? ?? ?????? ???????? ?? ??????? 80 – 125% ?? ?????? ????????????? ????????? • ???????????????? ??????? ??? ?????????? «????????????? ?????????» ????????? ? ??????? 5 ???? • ????? ?????????? ???? ???????????? ??????? ????? ? ???????????

    13. ????? ???????, ???????????? ????????? ????? ?????????? ?? ????? ??????????????????? ??? ??????????????????? ????????? ?? ???????????? ?????????? • ???????? ?????? ???????????? ?????????? ?? ????????? • ???????? ????? ???? ??????????? ????????, ?.?. ?????????????????? ???????? ?????, ??? ????????? ?????? ????? ?? ????????????? ???????????? ?????????? ?? ???????????? ????????, ???????????? ?????????? ???????

    14. ?????? ????????? ????????????? ????????? ???????????? ???????? ????????? ??????? ? ??? (??? ????? ? ???????? ?????????????? ?????????????? ? ?????? ????????????? ??????????? ?????????) ????????? ????????? ??????????? ????????-??????????? ?? ?????? ????? ????????? ???????????? ??????????

    15. ???????? ?????? ???????? ???????? ???????? ???? ?????????????????? ? ??????????? ????? - ?????????????

    16. ?????????????????? ??? ????????????? ????????? ???????????????, ???? ??? ??????????????? ???????????? ? ???? ?? ?????????????? (???????? ? ??????? ??????????) ????? ???????? ? ?????????? ???????? ???? ?????? ? ????? ???????, ??? ?? ????????????? ? ???????????? ? ???????? ?????????. EMEA, The rules governing medicinal products in the European Union. Investigation of Bioavailability and Bioequivalence, v. 3C, 1998, pp. 231–244 ???????????????? ????????????? ????????? — ??? ??????????????? ????????????? ?????????, ??????? ????? ????????? ?????????????? ??? ???????????? ? ??????? ????????????????? ????????. FDA, Electronic Orange Book. Approved Drug Products with Therapeutic Equivalence Evaluations, 20th Edition, 2000

    17. ??????????????? ??????????????? ????????????? ???????? ?????????????? ???????????? ??????? ?????????, ???? ?? ???????? ?? ?? ???????? ?????????? ?, ?? ??????????? ??????????? ????????????, ???????? ????? ?? ?????????????? ? ?????????????, ??? ? ???????? ?????????, ??? ????????????? ? ???????????? ??? ???????????. The rules governing medicinal products in the European Union. Investigation of Bioavailability and Bioequivalence, v. 3C, 1998, pp. 231–244 ?????????????? ?????????????? ????????????? ????????? ????? ????????? ?????? ? ??? ??????, ???? ??? ??????????????? ????????????, ????? ?????????? ??????????? ?????? ? ?????????? ??????? ????????????. FDA, Electronic Orange Book. Approved Drug Products with Therapeutic Equivalence Evaluations, 20th Edition, 2000

    18. ? 70-? ???? ??? ????? ? ???????? ???????? ???????? ?? ??????? (????????????) ??????, ? ????? ????????????? ?????????? ?????? ???????? ?????? ? ?????????? ???????? «????????» (generics), ???????? ?? ???? ???? • ?????????? ???????? ? ??? ?????????? «??????????? ?????????», ????? ????????????? ??????? ??????????? ??????????????? ??????? ??????? ???????? ?????????? ??? ???????? ?????? ????????, ??????? ?????????? ????? ??????? ????????????? ?????, ??? ???????????? ????????

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