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Dynamics of Prokaryotic Growth

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Dynamics of Prokaryotic Growth

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    1. Dynamics of Prokaryotic Growth Chapter 4

    2. Principles of Bacterial Growth Prokaryotic cells divide by binary fission Cell growth is exponential Doubling of population with each cell division Generation time Time it takes for population of cells to double a.k.a doubling time Varies among species

    3. Bacterial numbers can be estimated using the following equation: Nt = N0 x 2n (Nt ) number of cells in population (N0 ) original number of cells in the population (n) number of divisions

    4. Bacterial Growth in Nature Bacteria can sense changes in their environment Synthesize compounds useful for growth Cells produce multicellular associations to increase survivability

    5. Prokaryotes live in mixed communities Many interactions are cooperative Waste of one organism represents a nutrient for another Some cells compete for nutrients Synthesize toxic substance to inhibit growth of competitors

    6. Bacterial Growth Under Laboratory Conditions Cells in laboratory grown in closed or batch system No new input of nutrient and no release of waste Contrast to open or continuous system The population of cells in the culture increases in a predictable manner before declining Follows a pattern of stages called growth curve

    7. The Growth Curve

    8. Lag phase Number of cells does not increase Cells prepare for growth Log phase Period of exponential growth Doubling of population with each generation Produce primary metabolites Cells enter late log phase Synthesize secondary metabolites

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