bono
Uploaded by
11 SLIDES
251 VUES
110LIKES

Supplementary figs

DESCRIPTION

Supplementary figs. B Rucaprib uptake is not sodium dependent. S1. A [ 14 C] rucaprib accummulation in SW620 cells. C Rucaprib retention is associated with prolonged PARP inhibition. S2 Rucaparib metabolite PK. A. B. S2C.

1 / 11

Télécharger la présentation

Supplementary figs

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Supplementary figs

  2. B Rucaprib uptake is not sodium dependent S1 A [14C] rucaprib accummulation in SW620 cells C Rucaprib retention is associated with prolonged PARP inhibition

  3. S2 Rucaparib metabolite PK A B

  4. S2C

  5. Supplementary Table 1. Satellite rucaparib PK-PD in Capan-1 tumour-bearing mice Grey shading means values outside the standard curve.

  6. S3 A

  7. S3 B

  8. S3 C

  9. S3 D MX-1 study mouse weights

  10. S3 E Satellite PARP inhibition in MX-1 xenografts and liver 24 hr after single dose

  11. S3F

More Related