20 likes | 165 Vues
Interleukin-13 (IL-13) is a pleiotropic cytokine produced by activated Th2 cells in both humans and mice, primarily found as an unglycosylated protein of 132 amino acids with a molecular weight of 10 kDa. This important cytokine plays a crucial role in B cell proliferation and promotes IgE switching. The proliferative activity of IL-13 is tested in culture using the human erythroleukemic cell line TF-1. Understanding IL-13 and IL-4 receptor interactions is key for advancing therapeutic research in conditions influenced by Th2 responses.
E N D
IL-13 and IL-4 receptor combinations and binding SIGMA-ALDRICH
IL-13 and IL-4 receptor combinations and binding Interleukin-13 is a pleiotropic cytokine produced by activated Th2 cells in the mouse and human. IL-13 is secreted mainly as an unglycosylated protein of 132 amino acids with a molecular weight of 10 kDa. IL-13 induces B cell proliferation and also induces IgE switching. The proliferactive activity of human and mouse IL-13 is tested in culture using the human erythroleukemic cell line TF-1.