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MIF

This text explores the complex interactions between various cytokines, growth factors, and immune molecules in angiogenesis and immune modulation. Key players include IL-18, IFN-g, IL-2, and angiogenic factors such as VEGF and FGF. The involvement of adhesion molecules like ICAM-1 and P-selectin, as well as the anti-glucocorticoid effects of MIF, highlights the intricate balance between pro-inflammatory and anti-inflammatory signals. Understanding these pathways is crucial for developing therapeutic strategies targeting angiogenesis-related diseases.

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MIF

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  1. MIF

  2. MIF MMP IL-18 IFN-g IL-2 Angiogenesis VEGF, FGF, HGF IL-8, angipoietin-1 Stromal cell derived GF TNF, TGF (indirect) Angiostatic IL-12,IFN-a b g, PF4 Adhesion molecules ICAM-1,2 VAM-1 *b-integrin LAF-3 *P-selectin BMP MIF MIF Anti-glucocorticoid effects IL-1 & TNF-a TNF-a IL-1 IL-6 IL-7 IL-8 IL18 MIF angiopoietin-1 SDGF, FGF IgG IL-1 TNF-a GM-CSF IL-6 MIF IL-12 IL-18 IFN-g IL-2 IL-4 IL-6 IL-5 IL-17 MIF B Macrophage migration inhibitory factor MIF MIF effector T-cells MIF T T1,2 K Tc NK-IFN-g

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