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Integrated Biosurveillance Bioterrorism Preparedness Advanced Briefing for Industry Dec, 2004

. Anthrax Cases in DC. Flu Flu Flu. . . . Biosurveillance Challenges. Outbreak Detection ? Preparation, Response, RecoveryOutbreak Attribution: Natural vs Accidental vs Intentional. Data courtesy of Medstar

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Integrated Biosurveillance Bioterrorism Preparedness Advanced Briefing for Industry Dec, 2004

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    1. Integrated Biosurveillance & Bioterrorism Preparedness Advanced Briefing for Industry Dec, 2004

    4. Biosurveillance Projects ALADDIN Automated Link Analysis for Data-Mining of Distributed Information Phase II SBIR - Charles River Analytics Bayesian Belief Network, clinical & non-clinical data Health Information Data Mining for Early Identification of Bioterrorism Phase II SBIR Dynamics Technology AADP - Automated Anomaly Detection Processor, clinical & non-clinical data ESSENCE - Electronic Surveillance System for the Early Notification of Community-based Epidemics Worldwide daily syndromic surveillance of military outpatient clinic visits Evaluating incorporation of microbiology lab orders

    5. Biosurveillance Projects

    6. Biosurveillance Projects West Nile Virus

    8. Biosurveillance Projects - SARS Retrospective evaluation of data sources 10/02: enviro-clim lowest temperature in 62 yrs 11/02: media school, factory closings reported 2/03: socio-economic stores, parks deserted 2/03: transportation subways, buses deserted 2/03: telecom increased cell phone text messaging 2/03: internet PROMED unusual pneumonia WHO global alert issued 15 March 03 8 countries already involved, including US Ultimately >8400 people infected in 30 countries Case fatality rate up to 15%

    9. Biosurveillance Projects - Argus Objectives Policy & legal review Prospective prototype Response issues Disease models SARS/Avian influenza Rift Valley Fever Geographic areas Asia/Pacific East Africa Data sources News Media Transportation Telecommunication Enviroclimatic MOH Websites

    10. Established at Drexel University in Philadelphia, 2000 Rural partner in western PA - St Francis Univ Web-based training a major focus www.cimerc.org Chem-bio self assessment survey Incident scenario guidebook Educational and informational resources Argentina effort Spanish translations, evaluations Other potential collaboration

    11. CIMERC Self Assessment Survey

    12. CIMERC Problem Simulation Exercises 20 Scenarios Conventional Disasters Terrorism - Conventional Explosives Chemical Agent Release Infectious Disease Outbreak Contagious Disease Outbreak Nuclear/Radiological Incident

    13. Future Directions Biosurveillance Incorporation of other data sources animal, plant, biosensor Integration with response community National efforts & guidelines BioSense, CDC, NBIS/NBIC, Military Bioterrorism Preparedness Targeted, modular advanced distributed learning Novel, simulation-based response training

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