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HEARTBURN By Prof.MAHMOUD ABDEL-MONEIM CLINICAL PHARMCY DEPT FACULTY OF PHARMACY KAAU

HEARTBURN By Prof.MAHMOUD ABDEL-MONEIM CLINICAL PHARMCY DEPT FACULTY OF PHARMACY KAAU. DEFINITION Heartburn typically is described as a burning sensation or pain located in the lower chest. Symptoms usually occur soon after meals and when lying down at bedtime CAUSE:

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HEARTBURN By Prof.MAHMOUD ABDEL-MONEIM CLINICAL PHARMCY DEPT FACULTY OF PHARMACY KAAU

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  1. HEARTBURNBy Prof.MAHMOUD ABDEL-MONEIMCLINICAL PHARMCY DEPTFACULTY OF PHARMACY KAAU

  2. DEFINITION Heartburn typically is described as a burning sensation or pain located in the lower chest. Symptoms usually occur soon after meals and when lying down at bedtime CAUSE: Gastroesophageal reflux

  3. PRECIPITATING FACTORS -Hiatus hernia -Obesity -Large-sized meals -Immediate lying down after meals -Wearing tight fitting clothing -Smoking -Alcohol intake -Foods that irritate the esophagus (Tomato-based products; caffeine-containing beverages) -Foods that reduce LES tone (chocolate, mints, high fat foods ) -Drugs that reduce LES tone (CCBs; Nitrates ; Anti-cholinergic drugs; Oral contraceptives and estrogen )

  4. COMPLICATIONS ROLE OF PHARMACIST TREATMENT Lifestyle modification Drug therapy ( Antacids; H2HRA; PPIs ) Surgery

  5. CHOICE OF THERAPY -Mild\occasional symptoms -Persistent symptoms -Persistent symptoms + mucosal damage -Refractory disease

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