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Literature Research and Project Proposal

UBC iGEM Club – Brief Workshop. Literature Research and Project Proposal. Announcements. Team meeting: tomorrow 4pm MSL 226 Dr. Eric Lagally and Dr. Joanne Fox Presentation at M&I seminar: Friday 4pm 3:50pm at West Entrance Project Proposal: March 3 rd 4:30pm MSL 101

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Literature Research and Project Proposal

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  1. UBC iGEM Club – Brief Workshop Literature Research and Project Proposal

  2. Announcements • Team meeting: tomorrow 4pm MSL 226 • Dr. Eric Lagally and Dr. Joanne Fox • Presentation at M&I seminar: Friday 4pm • 3:50pm at West Entrance • Project Proposal: March 3rd 4:30pm MSL 101 • After reading break • 10-15 minutes each • Voting at the end

  3. Literature Research: iGEM • Goal: to build our own biological machine • New Application • Food/Energy: U Pavia, Ethanol? Whey not! • Foundational Advance: UA, Project BioBytes • Health/Medicine: Stanford, Immuni-T. coli • Environment: Cambridge, E. Chromi • Manufacturing • Information Processing: TU Delft, Bacterial Relay • Software Tools Biosensing is out

  4. Project proposal • Step 1. think outside the box • Daily life • News • In class

  5. Project proposal • Step 2. decide on a topic • New Application • Food/Energy • Foundational Advance • Health/Medicine • Environment • Manufacturing • Information Processing • Software Tools

  6. Idea research • Step 3. research, reserach, research • Google, Wikipedia • Scientific literature • Previous iGEM projects

  7. Search techniques • Keywords • Boolean searching • AND, NOT, OR • Focusing a search • Date • Author • Journal

  8. Approach Forward Backward

  9. Scientific literature search • Google scholar • Citation count and links • Web of Science • Defined search and filtering • Pubmed • Links to related topics

  10. Scientific literature search • Review articles • Read the appropriate section • Look at figures

  11. Previous iGEM projects • iGEM 2010: http://2010.igem.org/Main_Page • iGEM 04-09: http://2010.igem.org/Previous_iGEM_Competitions • Team abstracts • Team wiki • Presentation • Poster

  12. Idea research • Step 4. briefly record your search results

  13. Idea research • Step 5. discuss you idea with other people • Professors • Grad students • 2009 UBC iGEM team members • Peers

  14. 2 things to keep in mind • Computer modeling • Ethics

  15. Selection (tentative) • The specific project idea, well-contained, and its relation to the iGEM concept • The significance to the world if this idea came to fruition. • Any faculty on campus who could add expertise in the experimental phase of the project (for example, Dr. Lindsay Eltis in TB work, Dr.PhilHieter in yeast genetics, etc.) • A proposed budget based on the broad experiments you will need to conduct, including how much sequencing, how much PCR, etc. Ask me for help with this if you need it. The research part of the TLEF budget right now is $10,500. • Similar ideas being worked on in the world now, and previous attempts at this or similar ideas within the iGEM competition.

  16. Choosing a project (tentative) • Following all the presentations, we will discuss the ideas, and then vote by secret ballot. The winner will be chosen by a 2/3 majority. • If a 2/3 majority is not reached, then a run-off vote, also by secret ballot, between the closest contenders will be held, and the winner of that vote by simple majority (50%) will be chosen as the project for the summer.

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